Skip to main content
Advertisement
Welcome to PLOS Complex Systems

July 2, 2026

Welcome to PLOS Complex Systems

       

Image credit: PLOS

Interested in joining the board?

PLOS Complex Systems is looking for exceptional editors to join our team.

Apply

06/30/2026

Review

Component systems: Do null models explain everything?

Component systems — ensembles of realizations built from a shared repertoire of modular parts — are ubiquitous in biological, ecological, technological, and socio-cultural domains. From genomes to texts, cities, and software, these systems exhibit statistical regularities that often meet the bona fide requirements of laws in the physical sciences. The authors argue that the generality and simplicity of those laws are often due to basic combinatorial or sampling constraints. 

Image credit: Lagomarsino et al

Component systems: Do null models explain everything?

06/30/2026

research article

Deciphering and steering population-level response under spatial drug heterogeneity on microhabitat structures

Bacteria and cancer cells inhabit spatially heterogeneous environments, where migration shapes microhabitat structures critical for colonization and metastasis. The interplay between growth, migration, and spatial structure complicates the prediction of population responses to drug treatment, such as clearance or persistence, even under the same spatially averaged growth rate.

Image credit: Hu & Wood

Deciphering and steering population-level response under spatial drug heterogeneity on microhabitat structures

06/29/2026

research article

Mosquito dispersal in context

Mosquito dispersal plays an important role in mosquito ecology and mosquito-borne pathogen transmission. While reaction-diffusion and patch-based models with simple flux assumptions for emigration have played a predominant role in modeling mosquito dispersal, mosquito behavioral ecology – in particular, the process of searching for resources – is usually ignored by diffusion-based models. The authors set out to analyze mosquito movement using highly mimetic models, to see what they could learn from a different approach

Image credit: Sanchez et al

Mosquito dispersal in context

Get new content from PLOS Complex Systems in your inbox

PLOS Complex Systems | ISSN: 2837-8830 (online)