Key takeaways

  • Gazyva (obinutuzumab) is an immunotherapy drug used to treat chronic lymphocytic leukemia and follicular lymphoma in certain situations.
  • Gazyva infusions may be given with chemotherapy or other drugs, depending on your condition. After the first treatment cycle(s), you might have an infusion every 28 or 21 days.
  • Side effects of Gazyva can include infusion reactions, infections, low levels of certain blood cells, cough, and constipation or diarrhea.

The Food and Drug Administration (FDA) has approved Gazyva to treat the following:

Drug details

You’ll find key information about Gazyva here:

Gazyva is available only as a brand-name medication. It’s not currently available in biosimilar form.

A biosimilar is a medication that’s similar to a brand-name drug. A generic medication, on the other hand, is an exact copy of the active ingredient in a brand-name drug. Gazyva’s active ingredient is obinutuzumab.

Biosimilars are based on biologic drugs, which are made from parts of living organisms. Generics are based on regular medications made from chemicals. Biosimilars and generics also tend to cost less than brand-name drugs.

Gazyva can cause mild or serious side effects. The following lists contain some of the key side effects that may occur while taking Gazyva. These lists don’t include all possible side effects. Your side effects may vary depending on what condition you’re using Gazyva to treat.

For more information on the possible side effects of Gazyva, talk with your doctor. They can give you tips on how to deal with any side effects that may be concerning or bothersome.

Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. Sharing your experience helps make medications safer for everyone by giving doctors and researchers more information about how the drug works in real life. If you develop a side effect while taking Gazyva and want to tell the FDA about it, visit MedWatch or call 800-FDA-1088.

Mild side effects

Here is a partial list of mild side effects of Gazyva. To learn about other mild side effects, talk with your doctor or pharmacist, or view Gazyva’s prescribing information.

Mild side effects of Gazyva can include:

Most of these side effects may go away within a few days or a couple of weeks. But if they become more severe or don’t go away, talk with your doctor.

Serious side effects

Serious side effects from Gazyva aren’t common, but they can occur. Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life threatening or if you think you’re having a medical emergency.

Serious side effects and their symptoms can include:

  • severe infections such as pneumonia, which can cause symptoms that include:
    • fever
    • trouble breathing
    • cough
  • decreased level of white blood cells, which can cause the following symptoms:
    • infections that keep coming back or won’t go away
    • feeling tired
    • mouth sores
  • decreased level of platelets (blood cells that help your blood clot), causing symptoms that include:
  • tumor lysis syndrome (a buildup of harmful substances that are released when cancer cells break down quickly) with symptoms that can include:
    • fatigue
    • numbness or tingling
    • nausea, vomiting, or diarrhea
    • muscle cramps
    • seizures
    • irregular heart rate
  • severe infusion reaction, with symptoms that can include:
  • disseminated intravascular coagulation (problems with blood clotting and bleeding), which can cause symptoms such as:
    • bleeding from your nose, mouth, gums, rectum, or vagina
    • blood in your urine or stool
    • small dots or larger patches of bruising
    • pain, swelling, and warmth in a leg
    • chest pain
  • severe allergic reaction
  • hepatitis B virus reactivation, a flare-up of the hepatitis B virus if you’ve had it previously*
  • progressive multifocal leukoencephalopathy, a severe brain infection*

* Gazyva has boxed warnings for these side effects. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). For more information, see the “Gazyva precautions” section.

ALLERGIC REACTION

For some people, Gazyva can cause an allergic reaction. In general, symptoms of an allergic reaction can be mild or serious.

Allergic reactions may happen during a Gazyva infusion or right after. Sometimes, allergic reactions can also occur after your infusion is complete, such as hours or even days later. In this case, your symptoms may include chest pain, joint pain, or fever.

It’s rare to have an allergic reaction with your first dose of Gazyva. Usually, allergic reactions occur after you’ve already had at least one dose of the drug.

Ways to manage

For mild allergic reaction symptoms, such as a mild rash, call your doctor right away. They may recommend treatments to help manage your symptoms. They’ll also let you know whether you should keep taking the medication.

For severe allergic reaction symptoms, such as swelling or trouble breathing, call 911 or your local emergency number right away. These symptoms require immediate medical care because they can become life threatening. If you’ve had a serious allergic reaction to Gazyva, your doctor may recommend a different medication instead.

The Food and Drug Administration (FDA) approves prescription drugs such as Gazyva to treat certain conditions.

Gazyva for untreated chronic lymphocytic leukemia (CLL)

Gazyva is approved to treat chronic lymphocytic leukemia (CLL) that hasn’t yet been treated. In this case, Gazyva is given with another medication called chlorambucil (Leukeran).

CLL is a type of cancer that affects your white blood cells, causing them to become atypical. This can be dangerous because the atypical cells crowd out the healthy blood cells. CLL grows very slowly.

In clinical trials, Gazyva was shown to be an effective medication for treating CLL. For more information about Gazyva’s effectiveness, you can refer to the drug’s prescribing information or talk with your doctor.

Gazyva for follicular lymphoma that’s relapsed or refractory

Gazyva is approved to treat FL that has relapsed (come back) or is refractory (hasn’t improved) after treatment with rituximab (Rituxan).

You’ll first receive Gazyva along with bendamustine (Treanda). After treatment is complete, you may keep receiving Gazyva by itself.

FL is a type of non-Hodgkin lymphoma (NHL). This is a type of cancer that affects white blood cells called lymphocytes. These blood cells usually help you fight infections. With FL, your lymphocytes grow atypically, which can cause them to not work properly.

In a clinical trial, Gazyva was shown to be an effective treatment for relapsed or refractory FL. For details, refer to Gazyva’s prescribing information or talk with your doctor.

Gazyva for untreated follicular lymphoma

Gazyva is approved to treat FL that hasn’t yet been treated. In this case, Gazyva is used for these forms of FL:

  • Stage 2 bulky: Stage 2 means the cancer is in two or more groups of lymph nodes that are either both above, or both below, your diaphragm. (Your diaphragm is the muscle that’s beneath your lungs and helps you breathe.) So if you have stage 2 FL, you can have cancer in your neck and armpit area because these are both above the diaphragm. But you can’t have cancer in your neck and your abdomen. That’s because one of these areas is above the diaphragm and the other is below it. FL is considered bulky if you have a large mass in your chest. If your cancer is stage 2 bulky, you may need stronger treatments.
  • Stage 3: The cancer is on both sides of the diaphragm and may spread into the spleen.
  • Stage 4: The cancer has spread throughout your body. It may be in bone marrow or in other organs in your body.

You’ll use Gazyva along with chemotherapy, and then just Gazyva alone if your cancer goes into at least partial remission. This is when the cancer is still present, but there are fewer cancer cells in your body.

FL is a type of NHL. FL affects white blood cells called lymphocytes, which usually help you fight infections. With FL, your lymphocytes will grow atypically, which can cause them to not work properly.

For information about Gazyva’s effectiveness for this condition, you can refer to the drug’s prescribing information or talk with your doctor.

Off-label uses for Gazyva

In addition to the uses listed above, Gazyva may be used off-label for other purposes. Off-label drug use means prescribing a drug for a purpose other than what it’s been approved for by the FDA. Below are examples of off-label uses for Gazyva.

Gazyva for lupus nephritis

Gazyva isn’t currently FDA-approved to treat lupus nephritis. However, the drug may be prescribed off-label for this use.

The FDA granted Gazyva a breakthrough therapy designation for lupus nephritis in 2019. This means the drug may be more effective than current lupus nephritis treatments, but it needs to be studied more before it can be approved. A clinical trial has shown Gazyva to be effective for this condition, and the manufacturer has applied for FDA approval for lupus nephritis treatment.

Gazyva for DLBCL and other forms of lymphoma

Diffuse large B-cell lymphoma (DLBCL) is a type of cancer that affects your white blood cells. Currently, Gazyva isn’t FDA-approved to treat DLBCL or any other type of lymphoma besides FL and CLL. However, in some cases, Gazyva may be prescribed off-label for these uses.

Some studies have been done to test Gazyva in people with DLBCL. In one study, Gazyva was compared with rituximab. The results showed that the 3-year survival rates for people who took Gazyva or rituximab were similar.

In another study, Gazyva and the medications cyclophosphamide, doxorubicin, vincristine, and prednisone were given to people with DLBCL. The results showed that Gazyva can be added to other medications to be a potentially effective treatment for DLBCL.

If you have questions about using Gazyva for DLBCL or other types of lymphoma, check with your doctor.

Here are answers to some frequently asked questions about Gazyva.

How long does Gazyva (obinutuzumab) stay in your system?

Gazyva stays in your body for about 25 to 31 days. That’s why you usually receive it once every 21 to 28 days. By having the doses spread out, you’ll have the correct amount of medication in your body.

Will I need to take medication to prevent infections while I use Gazyva?

Usually, you won’t need to take medication to help prevent infections while you’re receiving Gazyva.

But your doctor will be checking your blood levels during your treatment. It’s possible that your level of neutrophils (a type of white blood cell) may drop too low and stay low for more than 1 week. If this happens, your doctor may have you take medication to prevent viral or fungal infections.

In some cases, your doctor may have you take a granulocyte-colony stimulating factor (G-CSF). This is a medication that helps increase the number of neutrophils in your body. If your neutrophil count gets too low, you’re at a higher risk of infection. By taking a GCSF, you can stimulate your immune system to help prevent infection during Gazyva treatment.

Talk with your doctor if you have any questions about medications you should take to help prevent infections during Gazyva treatment. They can also recommend other ways to avoid getting an infection.

Is Gazyva chemotherapy?

No. Gazyva isn’t chemotherapy. Gazyva belongs to a class of medications called monoclonal antibodies. Monoclonal antibody drugs are a kind of targeted treatment, meaning they work by acting on a specific area of your body. They also affect just that one area.

In comparison, chemotherapy affects all of the cells in your body, but especially fast-growing cells such as those that make up hair and line your stomach. Because chemotherapy affects many cells in your body, it can also cause many more side effects than targeted treatments.

Should I avoid getting any vaccines during Gazyva treatment?

You should avoid getting live vaccines while you’re receiving Gazyva and for a time after you finish your treatment.

Live vaccines have a weakened form of a virus or bacterium in them. Gazyva may weaken your immune system, so your body may not be able to fight the virus or bacterium in the live vaccine. This may cause you to develop an infection.

Examples of live vaccines include:

The manufacturer of Gazyva doesn’t mention whether it’s safe to get non-live (inactive) vaccines while using Gazyva. These vaccines don’t contain a live virus or bacterium.

Before you receive Gazyva, ask your doctor if you’re due for any vaccines. If you do need any vaccines, they may recommend getting them before you start treatment with Gazyva.

The Gazyva dosage your doctor prescribes will depend on several factors. These include:

  • the type of condition you’re using Gazyva to treat
  • other medical conditions you may have
  • if you’ve received Gazyva in the past and how your body responded to the drug

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Drug form and strength

Gazyva is a liquid solution that comes in a vial. It’s available in one strength: 1,000 milligrams per 40 milliliters (1,000 mg/40 mL).

A healthcare professional will give you Gazyva as an IV infusion. This is an injection into a vein that’s given over a set time. You’ll receive the infusions at your doctor’s office or in a hospital.

Dosage for untreated chronic lymphocytic leukemia (CLL)

Gazyva’s dosage for CLL is different for cycle 1 of treatment than for the rest of your treatment. You’ll first receive a loading dose. This helps you get enough medication into your body quickly so that it can start working as quickly as possible.

Gazyva treatment for CLL is given in 6 cycles, with 28 days in each cycle. Here’s the schedule:

  • Cycle 1, day 1: You’ll receive a 100-mg infusion of Gazyva over a 4-hour period.
  • Cycle 1, day 2: You’ll receive a 900-mg infusion of Gazyva. How long this and other doses take will depend on how your body reacts to the first dose. For example, if you have a mild reaction during the first dose, other doses may be given more slowly. This lets your body have more time to adjust to the drug.
  • Cycle 1, days 8 and 15: You’ll receive a 1,000-mg infusion of Gazyva.
  • Cycles 2 through 6, day 1: You’ll receive a 1,000-mg infusion of Gazyva.

You’ll receive chlorambucil (Leukeran) with Gazyva for CLL.

Dosage for follicular lymphoma that’s relapsed or refractory

Gazyva treatment for relapsed or refractory FL is given in six cycles, with 28 days in each cycle. You’ll take Gazyva along with bendamustine (Treanda) for all six cycles. You’ll receive a 1,000-mg infusion of Gazyva on these days:

  • Cycle 1: days 1, 8, and 15
  • Cycles 2 through 6: day 1

After your six cycles of Gazyva and bendamustine treatment, you’ll receive just Gazyva if your cancer has gone away, gotten smaller, or hasn’t gotten worse. You’ll have a 1,000-mg infusion of Gazyva every 2 months for up to 2 years.

If you don’t experience any severe infusion reactions, your infusions might be shortened from the usual 4-hour time to around 90 minutes, starting in cycle two.

Dosage for untreated follicular lymphoma

For untreated FL, you’ll receive Gazyva along with chemotherapy, and then just Gazyva alone if your cancer goes into at least partial remission. This is when the cancer is still present, but there are fewer cancer cells in your body.

Your treatment will be given in six to eight cycles, with 21 to 28 days in each cycle. Your dosage schedule will depend on what type of chemotherapy you’re receiving along with Gazyva:

  • Gazyva with bendamustine: You’ll have six cycles of treatment. Each cycle is 28 days long.
  • Gazyva with doxorubicin, cyclophosphamide, vincristine, and prednisone: You’ll have six cycles of treatment. Each cycle is 21 days long. After you finish the six cycles, you’ll have two additional cycles, during which you’ll receive only Gazyva. These cycles are 21 days long.
  • Gazyva with rituximab, cyclophosphamide, vincristine, and prednisone: You’ll have eight cycles of treatment. Each cycle is 21 days long.

You’ll receive a 1,000-mg infusion of Gazyva on these days:

  • cycle 1: on day 1
  • cycle 1: days 8 and 15
  • cycles 2 through 6 or 8: day 1

After your six or eight cycles of Gazyva treatment, you’ll receive just Gazyva if your cancer has gone away or improved. You’ll have a 1,000-mg infusion of Gazyva every 2 months for up to 2 years.

If you don’t experience any severe infusion reactions, your infusions might be shortened from the usual 4-hour time to around 90 minutes, starting in cycle 2.

About using Gazyva

  • If you miss a dose: If you miss an appointment for an infusion, reschedule it as soon as possible. The doctor’s office staff may have to adjust the timing of your future visits.
  • Length of use: If you and your doctor determine that Gazyva is safe and effective for you, you’ll likely take it long term. Usually, you’ll keep receiving Gazyva for up to a maximum of 2 years. But if your cancer worsens during this time, your doctor may stop your treatment.
  • How often it’s given: How often you receive Gazyva depends on what type of cancer you have and which treatment cycle you’re in. After your first treatment cycle, you’ll typically receive a Gazyva infusion every 28 days or every 21 days.
  • Taking Gazyva with food: You don’t need to eat while you’re getting your Gazyva infusion. However, your infusion may last many hours. So if you want to bring food or drinks with you, first talk with your doctor. They’ll be able to recommend what you can consume during your infusion appointment.

For more information about what to expect with Gazyva infusions, see the “How Gazyva is given” section.

As with all medications, the cost of Gazyva can vary. The actual price you’ll pay will depend on your insurance plan and your location.

If you need financial support to pay for Gazyva, help is available. Gazyva’s manufacturer offers some financial support options that you might qualify for. You can also call 866-4ACCESS (866-422-2377) to learn more.

Gazyva is not available in a generic form. A generic drug is an exact copy of the active ingredient in a brand-name medication. Generics tend to cost less than brand-name drugs.

Gazyva and Rituxan (rituximab) are both IV infusions prescribed for certain types of chronic lymphocytic leukemia and follicular lymphoma, but they’re used in different situations. Rituxan is also approved to treat other types of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, and other conditions.

Gazyva and Rituxan may be prescribed by themselves or with other drugs, depending on your condition and treatment plan.

These medications can cause very similar side effects and some different ones as well. Both drugs have boxed warnings about the risk of hepatitis B virus reactivation and a severe brain infection called progressive multifocal leukoencephalopathy.

Effectiveness for CLL

The use of Gazyva and Rituxan in treating CLL has been directly compared in a clinical study. Participants took Gazyva and chlorambucil (Leukeran) or Rituxan and chlorambucil to treat their CLL. The findings were as follows:

  • For people who received Gazyva and chlorambucil, their CLL worsened after 26.7 months.
  • For those who received Rituxan and chlorambucil, their CLL worsened after an average of 14.9 months.

Effectiveness for untreated FL

Gazyva and Rituxan were also compared in a clinical trial of people with FL who hadn’t been treated before. They received chemotherapy and either Gazyva or rituximab during the 38-month study.

  • FL worsened for about 18% of people who received Gazyva and chemotherapy.
  • FL worsened for 23% of those who received rituximab and chemotherapy.

Gazyva and Imbruvica (ibrutinib) are both brand-name drugs prescribed for certain types of CLL. They have some different uses as well:

  • Gazyva is also approved to treat some types of CLL and FL in certain situations.
  • Imbruvica is also approved to treat CLL with or without a change in your genes called 17p deletion, as well as certain other cancers and chronic graft-versus-host disease.

Gazyva is given as an IV infusion by a healthcare professional. Imbruvica comes as an oral capsule and tablet.

Gazyva and Imbruvica may be prescribed by themselves or with other drugs, depending on your condition and treatment plan. Gazyva can be used with Imbruvica to treat CLL that hasn’t been treated before.

These medications can cause some similar side effects, but some different ones as well. It’s important to note that Gazyva has boxed warnings about the risk of hepatitis B virus reactivation and a severe brain infection called progressive multifocal leukoencephalopathy. Imbruvica does not come with these warnings.

For details about how these drugs compare for your condition, you can talk with your doctor.

There’s no known interaction between Gazyva and alcohol. However, this medication can sometimes cause you to have low blood pressure. Alcohol may also cause your blood pressure to decrease. So taking Gazyva and drinking alcohol may cause your blood pressure to become too low, which can be dangerous.

If you drink alcohol, talk with your doctor about what amount is safe to drink during your Gazyva treatment.

Gazyva can interact with certain medications and vaccines, as shown in the following table. The drug isn’t known to interact with supplements or foods.

Before taking Gazyva, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

medications that can interact with Gazyvablood pressure medications, such as:
• amlodipine (Norvasc)
• diltiazem (Cartia XT)
• lisinopril (Prinivil)
• metoprolol (Toprol XL, Lopressor)
vaccines that can interact with Gazyvalive vaccines, such as:
• measles, mumps, rubella (MMR)
• nasal spray version of the flu shot
• smallpox
• chickenpox
• rotavirus
• yellow fever
• typhoid

This list does not contain all drugs that may interact with Gazyva. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Other drugs are available that can treat your condition. Some may be a better fit for you than others. If you’re interested in finding an alternative to Gazyva, talk with your doctor. They can tell you about other medications that may work well for you.

Depending on whether you take Gazyva for CLL or FL, the following drugs may be alternative options:

Note: Some of the drugs listed here are prescribed off-label to treat these specific conditions. Off-label use is when a drug that’s approved to treat one condition is used to treat a different condition.

A healthcare professional will give you Gazyva as an IV infusion at your doctor’s office or in the hospital. An infusion is an injection into a vein that’s given over a set time.

Gazyva infusions last about 4 hours at first, but later doses may take less time. In people with FL who haven’t had severe infusion reactions in the past, infusions may be shortened to about 90 minutes.

Make sure that you have a ride to and from your infusion appointments. You shouldn’t drive yourself home after an infusion because you may be dizzy or very tired.

Premedications

You may be given premedications before the infusion. These are drugs you take before your Gazyva doses to help prevent certain side effects, such as infusion reactions.

You’ll be given the premedications about 30 minutes to 1 hour before your dose of Gazyva. Which drugs you’re given depends on the type of cancer you have and if you had a reaction to Gazyva in the past.

With your first infusion of Gazyva, you’ll likely receive:

  • a steroid medication, such as dexamethasone (Decadron)
  • a medication to treat fever, such as acetaminophen (Tylenol)
  • an antihistamine medication, such as diphenhydramine (Benadryl)

If you tolerate your first dose of Gazyva well and don’t have an infusion reaction, your doctor may recommend only acetaminophen for future doses.

If you have a history of or are at high risk for tumor lysis syndrome (TLS), your doctor may also recommend allopurinol (Lopurin) as a premedication. And, they may recommend giving you fluids to help keep you hydrated. (TLS can cause a high level of uric acid and electrolytes in your blood. Premedication and fluids can help prevent these effects.)

Gazyva is a targeted treatment. This means it works on specific cells, called B cells, in your body.

How Gazyva works for CLL

The majority of CLL cases affect white blood cells called B-cells. When you have CLL, you have a lot of atypical white blood cells. They crowd out the healthy cells in your blood and bone marrow (the tissue inside bones that makes blood cells).

Gazyva works to treat CLL by binding specifically to B-cells and destroying them. This decreases the number of atypical B-cells in the blood and bone marrow and allows new cells to grow.

How Gazyva works for FL

FL begins in white blood cells called B-cells. Gazyva works to treat FL by binding specifically to B-cells and destroying them. This decreases the number of atypical B-cells that you have in your blood and bone marrow and allows new, healthy cells to grow.

It’s not known if Gazyva is safe to use during pregnancy. You and your doctor may weigh the benefits and risks of treatment if you’re considering this medication during pregnancy.

In animal studies, exposure to Gazyva during pregnancy caused offspring to have an increased risk of infection and certain allergic reactions. However, animal studies don’t always show exactly what will happen in humans.

If you take Gazyva during pregnancy, it’s likely that the drug will weaken the immune system of the baby. Because of this, babies who have been exposed to Gazyva shouldn’t be given live vaccines until their immune system regains strength. Your baby’s doctor will give your baby a blood test to make sure their immune system is strong enough for live vaccines.

If you’re pregnant or planning to become pregnant, talk with your doctor before starting Gazyva treatment. They can review the pros and cons of the drug with you.

If you’re able to become pregnant, you should use birth control during Gazyva treatment and for 6 months after your last dose.

If you’re taking Gazyva and your sexual partner(s) can become pregnant, talk with your doctor. They can review your birth control needs during and after your treatment.

It’s recommended not to breastfeed during Gazyva treatment and for 6 months after your last dose.

In studies of animals that were given Gazyva while pregnant, low levels of the drug were found in breast milk. Due to the risk of serious side effects if the drug passes into human breast milk, you should not breastfeed while receiving Gazyva. Your doctor can help recommend other feeding options for your child.

This drug comes with several precautions.

FDA warnings

Gazyva has a boxed warning, which is the most serious warning from the FDA. Boxed warnings alert doctors and patients about drug effects that may be dangerous.

Reactivation of hepatitis B virus (HBV): If you’ve had hepatitis B in the past, taking Gazyva can cause the HBV to become active again. This means that even if you’ve been treated for hepatitis B, the infection could come back. HBV reactivation can cause abdominal pain, yellowing of the skin and the whites of the eyes, serious conditions such as liver failure, and in some cases, death.

Your doctor will test your blood for HBV before you start using Gazyva. If you test positive, they may treat the HBV or monitor you more during and after your Gazyva use. If you have a history of HBV, talk with your doctor before using Gazyva. And if you develop any symptoms of HBV reactivation, tell your doctor right away.

Progressive multifocal leukoencephalopathy (PML): A rare viral brain infection called PML can occur during Gazyva treatment. Symptoms of PML can include:

  • confusion
  • dizziness
  • not able to walk or talk
  • changes in vision

PML can be life threatening. If you notice any symptoms of PML while taking Gazyva, tell your doctor right away. They’ll perform testing, such as brain scans, to determine if you have PML.

Other precautions

Before taking Gazyva, talk with your doctor about your health history. Gazyva may not be right for you if you have certain medical conditions or other factors affecting your health. These include:

  • any infections you have
  • history of cardiovascular problems
  • history of lung problems
  • your vaccination history
  • pregnancy or breastfeeding
  • history of allergic reaction to Gazyva or any of its ingredients
  • alcohol consumption

Note: For more information about the potential negative effects of Gazyva, see the “Gazyva side effects” section.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.