Yes, Repatha is still available as a medication used to help lower “bad” LDL cholesterol and reduce the risk of serious heart problems.

However, while the medication itself is still available, the way you take it is changing because some delivery devices are being phased out.

Repatha’s manufacturer, Amgen, is discontinuing two of the three original delivery methods. The changes are as follows:

  • Pushtronex system: The Pushtronex system, a device you wore for about 5 minutes to receive the medication, has been discontinued globally. This change is to improve the patient experience, as other options were faster and required fewer steps.
  • Prefilled syringe: The prefilled single-dose syringe was also discontinued in the first 3 months of 2026.

The main way people will take Repatha is through the SureClick Autoinjector. This is currently the most popular device for the medication. It is a handheld pen that delivers the dose in about 15 seconds. Many people prefer it because the needle is hidden inside a safety guard, which is helpful for those who prefer not to see the needle.

The Repatha website has instructions for using the SureClick autoinjector, a demo video, and other resources.

These changes are not due to safety or quality issues with the drug itself. The liquid medication in the auto injector is exactly the same as in the older devices. Amgen is simply focusing on the delivery method that is easiest and most convenient for users.

If you currently use the prefilled syringe or the Pushtronex system, you do not need to stop your treatment immediately. You can continue to use the medication you have as directed.

However, be sure to talk with your doctor before your next refill to get a new prescription for the SureClick Autoinjector.

Disclaimer: While Medical News Today strives for factual, comprehensive, and current information, this article is not a substitute for a licensed healthcare professional’s expertise. Always consult a doctor before taking or discontinuing any medication. Drug information is subject to change and may not cover all uses, directions, precautions, warnings, interactions, reactions, or adverse effects. The lack of a warning does not guarantee a drug’s safety, effectiveness, or appropriateness for all patients or specific uses. Learn more about our approach to content integrity.