Ozempic (semaglutide) is an injection prescribed to help manage type 2 diabetes and certain other associated conditions. It is possible that Ozempic can cause changes in mood and personality as a side effect. People might refer to this as ‘Ozempic personality’.
According to anecdotal reports on social media, personality and mood changes while taking Ozempic may include:
- increased anxiety
- increased depression
- lack of energy and enthusiasm
- lack of motivation
- loss of libido
- loss of interest in hobbies
It is possible that changes in how a person thinks, feels, and behaves while taking Ozempic are due to changes in brain chemistry and hormone levels, although there is no research to confirm this.
Neuroscientists are studying animals to learn more, but they currently believe that Ozempic affects dopamine pathways. Dopamine is also known as the “feel good” neurotransmitter — a chemical in the brain. If these dopamine pathways are changed, activities or things that once brought joy may not feel as enjoyable anymore.
More research with humans is necessary to better understand the connection between Ozempic and mood disorders.
People can also consider these other factors:
- a person’s history of mental health conditions, such as anxiety or depression, may make mood changes more likely
- weight loss, a common side effect of Ozempic, can also contribute to mood changes
- changes in mood may be more likely when a person first starts taking Ozempic
The FDA is evaluating
If a person has concerning changes in mood while using Ozempic, they must talk with their doctor. They may recommend adjusting the dosage or trying an alternative medication.
Disclaimer
Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication.
The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.