Briumvi’s dosage for multiple sclerosis (MS) is typically 450 mg every 6 months. Your dosing schedule may vary based on factors that include your symptoms and other medications you may be taking.

Briumvi (ublituximab-xiiy) is a prescription drug used to treat relapsing forms of MS. The drug comes as a solution for intravenous (IV) infusion administered into the veins. After two starting doses, Briumvi is given twice per year (every 6 months).

Briumvi is used in adults to treat:

The active ingredient in Briumvi is ublituximab-xiiy. Briumvi belongs to a group of drugs called anti-CD20 monoclonal antibodies.

This article describes the dosage of Briumvi, its strength, and how it’s given.

Your doctor will likely start you on a low dosage and adjust it over time to reach the right amount for you. They’ll ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly used or recommended for Briumvi. Be sure to take the dosage your doctor prescribes for you, as they’ll determine the best dosage to fit your needs. In some cases, doctors may adjust your dosage from those mentioned here.

Keep reading for more dosage details.

Briumvi form

Briumvi is available as a liquid solution given as an IV infusion.

Briumvi strength

Briumvi comes in one strength of 150 milligrams per 6 milliliters of solution (25 mg/mL) in a single-dose vial.

Briumvi is approved to treat relapsing forms of MS. Your doctor will likely prescribe the following recommended Briumvi infusion schedule:

  • First infusion: 150 mg
  • Second infusion: 450 mg, given 2 weeks after your first infusion
  • Maintenance infusions: 450 mg, given 24 weeks after your first infusion. You’ll continue to receive 450 mg by infusion every 24 weeks (6 months)

Always follow your prescribing doctor’s instructions. Notify them if you experience any side effects that may prevent you from continuing Briumvi treatment.

Briumvi is administered by a doctor, nurse, or other healthcare professional as an IV infusion (an injection into a vein given slowly over time). You’ll typically receive this medication in a clinical setting, such as a hospital or infusion clinic.

Briumvi infusion times vary — your first infusion usually takes at least 4 hours. Your second and maintenance infusions usually take about 1 hour or longer.

Infusion reactions and premedications

For some people, receiving medication in a vein can cause a reaction. Infusion reactions can be mild or serious and even life threatening.

To help reduce the risk of a reaction, your doctor may give you certain medications before each infusion. You’ll also stay with your infusion care team for at least 1 hour after your first and second infusions, so they can monitor you for symptoms of this side effect. If you have an infusion reaction, your doctor may stop the infusion.

Your doctor may also advise monitoring subsequent infusions, depending on how your body reacts to the first two infusions. If you have questions about infusion reactions, talk with your doctor.

How long does Briumvi treatment last?

Briumvi is usually a long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you’ll likely use it long term.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.