Systematic Review: Greater exposure to adverse #SocialDeterminants was associated with #neurobiological abnormalities in #Schizophrenia spectrum conditions, linking SDOHs to clinical outcomes and supporting equity-oriented approaches. https://ja.ma/3QMMjbb
JAMA Psychiatry
Book and Periodical Publishing
Chicago, Illinois 39,039 followers
A member of the JAMA Network, which includes JAMA, 11 specialty journals, and JAMA Network Open.
About us
JAMA Psychiatry strives to publish original, state-of-the-art studies and commentaries of general interest to clinicians and researchers in psychiatry, mental health, behavioral science, and allied fields. The journal seeks to inform its readers, to stimulate discussion into the nature, causes, treatment, and public health importance of mental illness, and to promote equity and justice for those affected by mental illness and for society.
- Website
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https://jamanetwork.com/journals/jamapsychiatry
External link for JAMA Psychiatry
- Industry
- Book and Periodical Publishing
- Company size
- 5,001-10,000 employees
- Headquarters
- Chicago, Illinois
- Founded
- 1919
- Specialties
- Psychiatry
Updates
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Targeted psychological and psychosocial interventions for #Schizophrenia, including avatar therapy, reduced the severity of #AuditoryHallucinations with small to medium effects and high acceptability. https://ja.ma/4fUuNfp
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Disrupted #gastrointestinal interoception predicted relapse and symptom severity in weight-restored females with #AnorexiaNervosa, supporting ingestible mechanosensory probes as scalable tools for monitoring and relapse prevention. https://ja.ma/4vQ3zLm
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Targeted psychological and psychosocial interventions for #Schizophrenia, including avatar therapy, reduced the severity of #AuditoryHallucinations with small to medium effects and high acceptability. https://ja.ma/4aAO0z2
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Disrupted gastrointestinal interoception predicted relapse and symptom severity in weight-restored females with #AnorexiaNervosa, supporting ingestible mechanosensory probes as scalable tools for monitoring and relapse prevention. https://ja.ma/4ovqZ6q
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📝 Narrative Review: Lithium, a long-standing mood stabilizer, demonstrates convergent neuroprotective and neurotrophic effects relevant to #Dementia and #AlzheimerDisease. Evidence across cellular, preclinical, human neuroimaging, and epidemiologic studies indicates that lithium upregulates anti-apoptotic proteins, boosts neurotrophic factors, inhibits tau-relevant kinase pathways, and stabilizes mitochondrial function. Low-dose lithium, which is below standard psychiatric dosing, preserves neuronal viability and gray matter, and cumulative exposure is associated with reduced dementia risk. Early clinical trials in mild cognitive impairment suggest favorable biomarker and cognitive outcomes, supporting prospective studies of low-dose lithium as a disease-modifying treatment. https://ja.ma/43ml1eu
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Across versions of ChatGPT, responses to psychotic prompts were frequently inappropriate or partially appropriate, raising safety concerns for users at risk for #psychosis. https://ja.ma/3SJyOJN
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📝 Narrative Review: Lithium, a long-standing mood stabilizer, demonstrates convergent neuroprotective and neurotrophic effects relevant to #Dementia and #AlzheimerDisease. Evidence across cellular, preclinical, human neuroimaging, and epidemiologic studies indicates that lithium upregulates anti-apoptotic proteins, boosts neurotrophic factors, inhibits tau-relevant kinase pathways, and stabilizes mitochondrial function. Low-dose lithium, which is below standard psychiatric dosing, preserves neuronal viability and gray matter, and cumulative exposure is associated with reduced dementia risk. Early clinical trials in mild cognitive impairment suggest favorable biomarker and cognitive outcomes, supporting prospective studies of low-dose lithium as a disease-modifying treatment. https://ja.ma/3QGFfg6
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This narrative review suggests mental disorders are statistical clusters of biopsychosocial properties, not sharply defined categories, mirroring concepts in species classification and supporting dimensional #MentalHealth frameworks. https://ja.ma/4epbWGU
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In adults with methamphetamine use disorder, mirtazapine reduced methamphetamine use by approximately two more days per month vs placebo, with no unexpected safety concerns. https://ja.ma/4vEdN1w
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