KEGG ORTHOLOGY: K04132

ORTHOLOGY: K04132

Entry

K04132                      KO

Symbol

CHRM4

Name

muscarinic acetylcholine receptor M4

Pathway

map04080

Neuroactive ligand-receptor interaction

map04725

Cholinergic synapse

map04810

Regulation of actin cytoskeleton

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04132  CHRM4; muscarinic acetylcholine receptor M4
09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04132  CHRM4; muscarinic acetylcholine receptor M4
09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    K04132  CHRM4; muscarinic acetylcholine receptor M4
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04132  CHRM4; muscarinic acetylcholine receptor M4
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Biogenic amine
   Acetylcholine (muscarinic)
    K04132  CHRM4; muscarinic acetylcholine receptor M4

Other DBs

GO:

0016907

Genes

HSA:	1132(CHRM4)

PTR:	466504(CHRM4)

PPS:	100979240(CHRM4)

GGO:	101145014(CHRM4)

PON:	100456753(CHRM4)

PPYG:

129008042(CHRM4)

NLE:	115830495(CHRM4)

HMH:	116476301(CHRM4)

SSYN:

129484172(CHRM4)

MCC:	574195(CHRM4)

MCF:	102138894(CHRM4)

MTHB:

126935753

MNI:	105471660(CHRM4)

CSAB:

103236497(CHRM4)

CATY:

105592796(CHRM4)

PANU:

101006709(CHRM4)

TGE:	112606774(CHRM4)

MLEU:

105554800(CHRM4)

RRO:	104668389(CHRM4)

RBB:	108519241(CHRM4)

TFN:	117079893(CHRM4)

PTEH:

111544991(CHRM4)

CANG:

105527114(CHRM4)

CJC:	100385016(CHRM4)

SBQ:	101046353(CHRM4)

CIMI:

108283268 108304872(CHRM4)

ANAN:

105717329(CHRM4)

CSYR:

103252719(CHRM4)

MMUR:

105885226(CHRM4)

LCAT:

123642649(CHRM4)

PCOQ:

105811087(CHRM4)

OGA:	100957661(CHRM4)

MMU:	12672(Chrm4)

MCAL:

110288551(Chrm4)

MPAH:

110319039(Chrm4)

RNO:	25111(Chrm4)

MCOC:

116090486(Chrm4)

ANU:	117704181(Chrm4)

ASYL:

127684453(Chrm4)

MUN:	110549888(Chrm4)

CGE:	100752496(Chrm4)

MAUA:

101839693(Chrm4)

PROB:

127222234(Chrm4)

PLEU:

114699703(Chrm4)

MORG:

121437584(Chrm4)

MFOT:

126489785

AAMP:

119815573(Chrm4)

NGI:	103748793(Chrm4)

HGL:	101726411(Chrm4)

CPOC:

100714736(Chrm4)

CCAN:

109692003(Chrm4)

DORD:

105996053(Chrm4)

DSP:	122105184(Chrm4)

PLOP:

125361214(Chrm4)

NCAR:

124960171

MMMA:

107134589(Chrm4)

ITI:	101957443(Chrm4)

OCU:	100008791(CHRM4) 127486600

OPI:	101530695(CHRM4)

TUP:	102499516(CHRM4)

GVR:	103588713(CHRM4)

CFA:	611314(CHRM4)

CLUD:

112663296(CHRM4)

VVP:	112924093(CHRM4)

VLG:	121501518(CHRM4)

NPO:	129500068(CHRM4)

AML:	100479242(CHRM4)

UMR:	103672391(CHRM4)

UAH:	113264986(CHRM4)

UAR:	123799574(CHRM4)

ELK:

111150135

LLV:

125078317

MPUF:

101682926(CHRM4)

MNP:	132008205 132008379

MLK:	131812024(CHRM4)

NVS:	122912880(CHRM4)

ORO:	101383947(CHRM4)

EJU:	114215143(CHRM4)

ZCA:	113913965(CHRM4)

MLX:	118015567(CHRM4)

NSU:	110575760(CHRM4)

LWW:	102742934(CHRM4)

FCA:	101088360(CHRM4)

PYU:	121043474(CHRM4)

PCOO:

112865504(CHRM4)

PBG:	122483754(CHRM4)

PVIV:

125176300(CHRM4)

LRUF:

124506450

LGF:	123602270(CHRM4)

AJU:

106978068

PTG:	102955317(CHRM4)

PPAD:

109245090(CHRM4)

PUC:

125934109

PLEZ:

122200958(CHRM4)

HHV:	120228491(CHRM4)

BTA:	512928(CHRM4)

BOM:	102268436(CHRM4)

BIU:	109569900(CHRM4)

BBUB:

102408993(CHRM4)

BBIS:

104990333(CHRM4)

CHX:	102168474(CHRM4)

OAS:	101114554(CHRM4)

BTAX:

128060443(CHRM4)

CSUM:

138093045(CHRM4)

ODA:	120876931(CHRM4)

CCAD:

122449503(CHRM4)

MREE:

136175090(CHRM4)

OVR:	110130075(CHRM4)

MBEZ:

129554066(CHRM4)

SSC:	100516483(CHRM4)

CFR:	102505450(CHRM4)

CBAI:

105076467(CHRM4)

CDK:	105106860(CHRM4)

VPC:	102536918(CHRM4)

BACU:

103009712(CHRM4)

BMUS:

118899863(CHRM4)

LVE:	103084511(CHRM4)

OOR:	101286932(CHRM4)

LALB:

132525176(CHRM4)

DLE:	111183985(CHRM4)

PCAD:

102988881(CHRM4)

PSIU:

116758194(CHRM4)

NASI:

112402348(CHRM4)

ECB:	102147631(CHRM4)

EPZ:	103566518(CHRM4)

EAI:	106843991(CHRM4)

MYB:	102248536(CHRM4)

MYD:	102773569(CHRM4)

MMYO:

118665086(CHRM4)

MLF:	102431589(CHRM4)

MDT:	132241216(CHRM4)

MYUM:

139018907(CHRM4)

PKL:	118713110(CHRM4)

EFUS:

103290847(CHRM4)

MNA:	107530288(CHRM4)

DRO:	112303426(CHRM4)

SHON:

118974536(CHRM4)

AJM:	119064490(CHRM4)

PDIC:

114500774(CHRM4)

PHAS:

123810066(CHRM4)

MMF:	118628391(CHRM4)

PPAM:

129081514(CHRM4)

HAI:	109390187(CHRM4)

RFQ:	117031267(CHRM4)

PALE:

102896255(CHRM4)

PGIG:

120606853(CHRM4)

PVP:	105290017(CHRM4)

RAY:	107511865(CHRM4)

MJV:	108406805(CHRM4)

TOD:	119254523(CHRM4)

SARA:

101544296(CHRM4)

SFUM:

130016682(CHRM4)

SETR:

126017646(CHRM4)

LAV:	100676992(CHRM4)

TMU:

101345157

ETF:	101641746(CHRM4)

DNM:	101415818(CHRM4)

MDO:	100011680(CHRM4)

GAS:	123251971(CHRM4)

SHR:	100929864(CHRM4)

AFZ:

127540382

PCW:	110224008(CHRM4)

TVP:	118854423(CHRM4)

PBRV:

138163878(CHRM4)

OAA:	100085485(CHRM4)

TACU:

119943442(CHRM4)

GGA:	423195(CHRM4)

PCOC:

116229170(CHRM4)

MGP:	100549620(CHRM4)

CJO:	107314777(CHRM4)

TPAI:

128086316(CHRM4)

LMUT:

125695205(CHRM4)

NMEL:

110400960(CHRM4)

APLA:

101794923(CHRM4)

ACYG:

106043487(CHRM4)

CATA:

118244472(CHRM4)

AFUL:

116489871(CHRM4)

TGU:	100220023(CHRM4)

LSR:	110472075(CHRM4)

SCAN:

103826681(CHRM4)

PMOA:

120500501(CHRM4)

OTC:	121332620(CHRM4)

PRUF:

121349489(CHRM4)

ATRC:

139590181(CHRM4)

GFR:	102033258(CHRM4)

FAB:	101809126(CHRM4)

OMA:	130253786(CHRM4)

PHI:	102100125(CHRM4)

PMAJ:

107206414(CHRM4)

CCAE:

111930184(CHRM4)

CCW:	104698130(CHRM4)

CBRC:

103620748(CHRM4)

ACOE:

138110778(CHRM4)

ETL:	114059091(CHRM4)

ZAB:	102065508(CHRM4)

ZLE:	135448303(CHRM4)

ACHL:

103797384(CHRM4)

SVG:	106856487(CHRM4)

MMEA:

130573025(CHRM4)

HRT:	120754184(CHRM4)

SATI:

136362530(CHRM4)

CCIC:

134045314(CHRM4)

FPG:	101913200(CHRM4)

FCH:	102045917(CHRM4)

CCRI:

104162936(CHRM4)

NNT:	104400153(CHRM4)

SHAB:

115606877(CHRM4)

ACUN:

113480825(CHRM4)

TALA:

104359824(CHRM4)

ACHC:

115336241(CHRM4)

HALD:

104316121

HLE:	104839684(CHRM4)

AGEN:

126049449

HHAR:

128139534(CHRM4)

GCL:

127016655

CSTI:

104555967(CHRM4)

LDI:	104350269(CHRM4)

MNB:	103782075(CHRM4)

DPUB:

104297442(CHRM4)

PPUS:

135176333(CHRM4)

AVIT:

104274462(CHRM4)

BRHI:

104499380(CHRM4)

EGZ:	104134081(CHRM4)

NNI:	104020374(CHRM4)

PCRI:

104031635(CHRM4)

PCAO:

104046364

PADL:

103921716(CHRM4)

AFOR:

103897488(CHRM4)

FGA:	104073083(CHRM4)

GSTE:

104259526(CHRM4)

CLV:	102089245(CHRM4)

MUI:	104537756(CHRM4)

PGUU:

104468593(CHRM4)

PLET:

104620986(CHRM4)

EHS:	104516753(CHRM4)

CMAC:

104473425(CHRM4)

CUCA:

104067289(CHRM4)

TEO:	104384525(CHRM4)

BREG:

104634336(CHRM4)

OHA:	104328098(CHRM4)

ACAR:

104528911

CPEA:

104390419(CHRM4)

CVF:	104295864(CHRM4)

RTD:	128908761(CHRM4)

AAM:	106498177(CHRM4)

AROW:

112977828(CHRM4)

NPD:	112943829(CHRM4)

TGT:	104572231(CHRM4)

DNE:	112987569(CHRM4)

SCAM:

104150367(CHRM4)

ASN:	102373825(CHRM4)

AMJ:	102574546(CHRM4)

CPOO:

109321598(CHRM4)

GGN:	109298910(CHRM4)

PSS:	102447244(CHRM4)

CMY:	102939163(CHRM4)

CCAY:

125638652(CHRM4)

DCC:	119857724(CHRM4)

CPIC:

101934434(CHRM4)

TST:	117877220(CHRM4)

CABI:

116821706(CHRM4)

MRV:	120402927(CHRM4)

ACS:	100553418(chrm4)

ASAO:

132768173(CHRM4)

PVT:	110081801(CHRM4)

SUND:

121919040(CHRM4)

PBI:	103052687(CHRM4)

PMUR:

107288590(CHRM4)

CTIG:

120314250(CHRM4)

TSR:	106545970(CHRM4)

PGUT:

117665516(CHRM4)

APRI:

131189257(CHRM4)

PTEX:

113439075(CHRM4)

NSS:	113414247(CHRM4)

VKO:	123026715(CHRM4)

PMUA:

114596001(CHRM4)

PRAF:

128413196(CHRM4)

ZVI:	118085081(CHRM4)

HCG:	128335670(CHRM4)

GJA:	107107913(CHRM4)

STOW:

125427438(CHRM4)

EMC:	129324907(CHRM4)

XLA:	108713768(chrm4.L) 108715244(chrm4.S)

XTR:	100127705(chrm4)

NPR:	108797320(CHRM4)

RTEM:

120917129(CHRM4)

BBUF:

120980212(CHRM4)

BGAR:

122920738(CHRM4)

PWL:	138262364 138262365 138283700(CHRM4)

MUO:	115468828(CHRM4)

GSH:	117351966(CHRM4)

DRE:	100004742(chrm4b) 100150701(chrm4a)

SRX:	107720794 107722408 107740880 107742565

SANH:

107656177(chrm4) 107670211 107673223 107682891 107703274

SGH:	107554636 107559969 107560117 107569698

CCAR:

109050617 109050619 109055877 109067154 109095854

CAUA:

113043718 113051452 113066697 113106108

CGIB:

127946974 127962186 128014603 128016805

PTET:

122331161(chrm4b) 122349173(chrm4a)

LROH:

127156396(chrm4b) 127168231(chrm4a)

OMC:	131534074(chrm4b)

PPRM:

120475359(chrm4b) 120493456(chrm4a)

RKG:	130073719(chrm4b) 130078260(chrm4a)

MAMB:

125246819(chrm4b) 125265005(chrm4a)

CIDE:

127507477 127516337

CERY:

137014612(chrm4b) 137030382(chrm4a)

MASI:

127416738 127435928 127445333

TROS:

130552123(chrm4b) 130559086(chrm4a)

TDW:	130414267(chrm4b) 130424197(chrm4a)

MANU:

129434178(chrm4b) 129445497(chrm4a)

PDAB:

135778845(chrm4a) 135781166 135787798

IPU:	108259214(chrm4a)

IFU:	128603116(chrm4a)

PHYP:

113546707(chrm4)

SMEO:

124379984(chrm4a)

TFD:	113634234(chrm4a)

TVC:	132838757(chrm4a)

CGAR:

128519112(chrm4a)

NGRA:

132875268(chrm4a)

TRN:	134304254(chrm4a)

AMEX:

103043196(chrm4a)

CMAO:

118817660(chrm4a)

EEE:	113585613(chrm4)

CHAR:

105889062(chrm4a) 105892363(chrm4b)

SPIL:

134095824(chrm4a)

TRU:	101068602 101072036(chrm4)

TFS:	130522767(chrm4a) 130535756(chrm4b)

TNG:	GSTEN00025705G001 GSTEN00027047G001

LCO:	104937647 104939235

NCC:	104944525 104959784

TBEN:

117476186 117477441(chrm4a)

CGOB:

115005369 115021681

PGEO:

117456335(chrm4a)

GACU:

117539328 117546063

EMAC:

134859319(chrm4b) 134860662(chrm4a)

ELY:	117249879(chrm4a) 117262688(chrm4b)

EFO:	125885083(chrm4a) 125887853(chrm4b)

PLEP:

121938489 121962873(chrm4a)

SLUC:

116042137 116051799(chrm4a) 116055786

ECRA:

117939483(chrm4a) 117948961(chrm4b)

ESP:	116673693(chrm4)

PFLV:

114551114 114560543

GAT:	120808846(chrm4b) 120818432

PPUG:

119196053(chrm4b) 119209632(chrm4a)

AFB:	129108642(chrm4b) 129111859(chrm4a)

CLUM:

117732818(chrm4b) 117744434(chrm4a)

PSWI:

130194937(chrm4b)

CANA:

137793960(chrm4a) 137799720(chrm4b)

CVE:	137868128(chrm4a) 137881399(chrm4b)

MSAM:

119893703(chrm4b) 119900691

SCHU:

122872198(chrm4a) 122874406(chrm4b)

CUD:	121506330(chrm4a) 121515594(chrm4b)

SPUL:

138603645(chrm4a) 138612600(chrm4b)

LMIX:

132959507(chrm4a) 132973016(chrm4b)

ALAT:

119015645(chrm4a) 119024231(chrm4b)

ASTR:

137591504(chrm4a) 137593468(chrm4b)

MZE:	101471221 101472526

ONL:	100691419 100699420

OAU:	116310404(chrm4a) 116329717(chrm4b)

OLA:	101170675(chrm4) 101174568

OML:	112142019(chrm4a) 112151885(chrm4b)

CSAI:

133425250(chrm4a) 133444877(chrm4b)

XMA:	102235242 106699859(chrm4)

XCO:	114140782 114152508(chrm4)

XHE:	116715536 116731490(chrm4)

PRET:

103466797(chrm4) 103477206

PFOR:

103132571 103148625(chrm4)

PLAI:

106955220 106964541

PMEI:

106909896 106921944

GAF:	122827170(chrm4a) 122836174(chrm4b)

PPRL:

129365378(chrm4b) 129378780(chrm4a)

CVG:	107100526(chrm4) 107103213

CTUL:

119775037(chrm4a) 119781653(chrm4b)

GMU:	124859719(chrm4b) 124861730(chrm4a)

NFU:	107384537 107388564(chrm4)

KMR:	108228824(chrm4b) 108241822(chrm4a)

ALIM:

106527975(chrm4) 106534512

NWH:	119415948(chrm4b) 119429180(chrm4a)

AOCE:

111579041 111585666

EJA:	138192553 138213939

BFRE:

138631962(chrm4a) 138636438(chrm4b)

MCEP:

125000614 125014879(chrm4b)

CSEM:

103379693(chrm4) 103389423

POV:	109639010(chrm4) 109645231

SSEN:

122760776(chrm4a) 122775791(chrm4b)

SSOE:

131469554(chrm4b) 131475318(chrm4a)

HHIP:

117777378(chrm4a)

HSP:	118103176 118109280(chrm4b)

PPLT:

128431067(chrm4a) 128444633(chrm4b)

SMAU:

118311276 118314788

LCF:	108880227 108885235 108892233

SDU:	111233207 111233738(chrm4)

SLAL:

111651267 111669615 111670361(chrm4)

XGL:	120793284(chrm4b) 120798191(chrm4a)

HCQ:	109514780(chrm4) 109518202

SSCV:

125970135 125989435(chrm4a)

SBIA:

133494613(chrm4a)

PEE:	133405667(chrm4a)

PTAO:

133483332(chrm4a)

BPEC:

110158694 110175638

MALB:

109951519

BSPL:

114843475 114857687(chrm4b)

SJO:	128354053 128358902(chrm4b)

SSCO:

133976407(chrm4a) 133981801(chrm4b)

GMH:	115546658 115550686

SASA:

106560739 106561947 106587108

STRU:

115167529

OTW:	112218297(chrm4b) 112249008

OMY:	110491741(chrm4b) 110526197

OGO:	124011446(chrm4b) 124033921 124035893

ONE:	115112073 115134808

OKI:	109867655 109885336(chrm4)

OKE:	118393681 118396097(chrm4b)

OMM:	135505286 135508862(chrm4b) 135557279

OCLA:

139377421 139411316

SALP:

111960944 111969217 111974520

SNH:	120025354 120055812 120066610(chrm4b)

CCLU:

121531206(chrm4b) 121559956 121561505

ELS:	105018677 105027322(chrm4)

SFM:	108929069 108941033(chrm4)

PKI:	111846693 111858217

AANG:

118214948 118226932(chrm4a)

AROT:

135242329 135255307(chrm4a)

CCOG:

133111657 133130830(chrm4a)

LOC:	102692176(chrm4)

PSPA:

121295051 121330258

ARUT:

117432275 117434803

PSEX:

120530366(chrm4a)

LCM:	102345705(CHRM4)

CMK:	103186021(chrm4a)

RTP:	109938848(chrm4a)

CPLA:

122557949(chrm4a)

HOC:	132824152(chrm4a)

LERI:

129705863(chrm4a)

PMRN:

116940023(CHRM4) 116945452 116956383

LRJ:	133350202 133351308 133360412

BFO:

118426236

LPIC:

129258968 129261678 129264093 129265648 129266715 129267017 129275272 129282741

APLC:

110980874 110988539

ARUN:

117290587 117292853 117293786 117305156

AAMU:

139936040 139949400 139949925

AFIL:

140149612 140162291 140163992 140164397

DWI:

PCLA:

VJA:

LSAX:

GAE:

OED:

MYI:

PMAX:

AIRR:

RPHI:

DPOL:

MAEA:

128204203 128204304 128205185 128205965 128244911 128244912

LLON:

135488293

HMG:

105843373

» show all

Reference

PMID:3037705

Authors

Bonner TI, Buckley NJ, Young AC, Brann MR

Title

Identification of a family of muscarinic acetylcholine receptor genes.

Journal

Science 237:527-32 (1987)
DOI:10.1126/science.3037705

Sequence

[rno:25111]

LinkDB

DBGET integrated database retrieval system