Victor Reus, MD
Professor Emeritus
Psychiatry
School of Medicine

He is a former Medical Director of the Langley Porter Hospital and is Co-Principal Investigator or Co-Investigator on a number of extramural supported research grants, as well as an editor of Focus:the Journal of Life Long Learning in Psychiatry and a former editor of Faculty 1000 reviews. He has received the APA/NIMH Vestermark Award for excellence as a psychiatric educator and the Distinguished Service in Psychiatry Award from the American College of Psychiatrists, served on the DSM-5 Oversight and Clinical and Public Health Committees, is an Emeritus Director and Vice-Chair of the American Board of Psychiatry and Neurology (ABPN) and former Chair of the Psychiatry Residency Review Committee (RRC) for the Accreditation Council for Graduate Medical Education (ACGME), and has been listed in successive editions of The Best Doctors in America and America's Top Doctors for over thirty-five years. In 2016 he was Chair of the Board of Directors of the Accreditation Council for Continuing Medical Education (ACCME), the accrediting organization for 2000 providers, offering 1 million hours of CME annually to physicians. Dr. Reus currently serves as Chair of the Practice Guideline Writing Group for the American Psychiatric Association, and has been the Chair of the UCSF Human Research Institutional Review Board (Parnassus) for over twenty years. He has authored the chapter on psychiatric disorders and their treatment for Harrison's Principles of Internal Medicine for the last 9 editions, and has published over 330 peer reviewed articles and chapters, with a particular emphasis on the biology and genetics of mood disorders, resulting in an h-index of 87 and over 30,000 citations (Google Scholar). 78 papers (GS) have received over 100 citations each, with 3 papers designated by Web of Science as in the top 1% of all cited papers for the field and publication year. A textbook, "The Psychopharmacology of Neurologic Disease", was published by Elsevier Press as Volume 165 of The Handbook of Clinical Neurology series in November 2019.

• Kynurenine Metabolism is Associated with Antidepressant Response to Selective Serotonin Reuptake Inhibitors.
  bioRxiv : the preprint server for biology 2025 Rampersaud R, Suneson K, Wu GWY, Reus VI, Lindqvist D, Ho TC, Meyerhoff DJ, Irwin MR, Wolkowitz OM, Mellon SH, Brundin L
• Predicting Diagnostic Conversion From Major Depressive Disorder to Bipolar Disorder: An EHR Based Study From Colombia.
  Bipolar disorders 2024 Service SK, De La Hoz JF, Diaz-Zuluaga AM, Arias A, Pimplaskar A, Luu C, Mena L, Valencia-Echeverry J, Ramírez MC, Bearden CE, Sabatti C, Reus VI, López-Jaramillo C, Freimer NB, Olde Loohuis LM
• Dispositional optimism predicts antidepressant treatment response in major depressive disorder: potential relevance for positive psychology interventions
  Journal of Positive Psychology 2024 Coopersmith A, Wolkowitz O, Mellon S, Wu G, Rampersaud R, Hansen N, Dutcher E, Reus VI, Mayer S
• Phenotype harmonization and analysis for The Populations Underrepresented in Mental illness Association Studies (the PUMAS Project).
  medRxiv : the preprint server for health sciences 2024 Ramirez-Diaz AM, Diaz-Zuluaga AM, Stroud RE, Vreeker A, Bitta M, Ivankovic F, Wootton O, Whiteman CA, Mountcastle H, Jha SC, Georgakopoulos P, Kaur I, Mena L, Asaaf S, de Souza Rodrigues AL, Ziebold C…
• Serum brain-derived neurotrophic factor, Val66Met polymorphism and open-label SSRI treatment response in Major Depressive Disorder.
  Psychoneuroendocrinology 2024 Smit AJT, Wu GWY, Rampersaud R, Reus VI, Wolkowitz OM, Mellon SH
• Geospatial investigations in Colombia reveal variations in the distribution of mood and psychotic disorders.
  Communications medicine 2024 Song J, Ramírez MC, Okano JT, Service SK, de la Hoz J, Díaz-Zuluaga AM, Upegui CV, Gallago C, Arias A, Sánchez AV, Teshiba T, Sabatti C, Gur RC, Bearden CE, Escobar JI, Reus VI, Jaramillo CL, Freimer …
• Circulating cell-free mitochondrial DNA levels and glucocorticoid sensitivity in a cohort of male veterans with and without combat-related PTSD.
  Translational psychiatry 2024 Blalock ZN, Wu GWY, Lindqvist D, Trumpff C, Flory JD, Lin J, Reus VI, Rampersaud R, Hammamieh R, Gautam A, SBPBC, Doyle FJ, Marmar CR, Jett M, Yehuda R, Wolkowitz OM, Mellon SH
• Predicting diagnostic conversion from major depressive disorder to bipolar disorder: an EHR based study from Colombia.
  medRxiv : the preprint server for health sciences 2023 Service SK, De La Hoz J, Diaz-Zuluaga AM, Arias A, Pimplaskar A, Luu C, Mena L, Valencia J, Ramírez MC, Bearden CE, Sabbati C, Reus VI, López-Jaramillo C, Freimer NB, Loohuis LMO
• Integrated analysis of proteomics, epigenomics and metabolomics data revealed divergent pathway activation patterns in the recent versus chronic post-traumatic stress disorder
  Brain Behav Immun 2023 Muhle S, Gautam A, Misganaw B......PTSD System Biology Consortium (Reus V)....Yehuda R, Hammamieh R, Jett M
• Shorter telomere length predicts poor antidepressant response and poorer cardiometabolic indices in major depression.
  Scientific reports 2023 Rampersaud R, Wu GWY, Reus VI, Lin J, Blackburn EH, Epel ES, Hough CM, Mellon SH, Wolkowitz OM
• Molecular Signatures of Post-traumatic Stress Disorder in War-zone-exposed Veteran and Active Duty Soldiers
  Cell Reports Medicine 2023 Muhie S, Gautam A, Yang R.....PTSD Systems Consortium (Reus V)...Jett M
• Dimensions of childhood adversity differentially affect biological aging in major depression.
  Translational psychiatry 2022 Rampersaud R, Protsenko E, Yang R, Reus V, Hammamieh R, Wu GWY, Epel E, Jett M, Gautam A, Mellon SH, Wolkowitz OM
• Geospatial Analysis Reveals Distinct Hotspots of Severe Mental Illness
  medRxiv 2022 Janet Song, Mauricio Castaño Ramírez, Justin Okano, Susan K. Service, Juan de la Hoz, Ana M Díaz-Zuluaga, Cristian Vargas Upegui, Cristian Gallago, Alejandro Arias, Alexandra Valderrama Sánchez, Terri…
• Recommendations for the Usage of Ketamine and Esketamine.
  The American journal of psychiatry 2021 Reus VI
• Blood-based mitochondrial respiratory chain function in major depression.
  Translational psychiatry 2021 Fernström J, Mellon SH, McGill MA, Picard M, Reus VI, Hough CM, Lin J, Epel ES, Wolkowitz OM, Lindqvist D
• Development and Implementation of a Chief Resident for Research Role in a Psychiatry Residency Training Program.
  Advances in medical education and practice 2021 Hwong AR, Morgan S, Young CA, Besterman AD, Jacob M, Williams J, Reus VI, Mathews CA, Hung E, Voglmaier S
• Ozanimod as Induction and Maintenance Therapy for Ulcerative Colitis.
  The New England journal of medicine 2021 Sandborn WJ, Feagan BG, D'Haens G, Wolf DC, Jovanovic I, Hanauer SB, Ghosh S, Petersen A, Hua SY, Lee JH, Charles L, Chitkara D, Usiskin K, Colombel JF, Laine L, Danese S, True North Study Group
• Abnormal levels of mitochondrial proteins in plasma neuronal extracellular vesicles in major depressive disorder.
  Molecular psychiatry 2021 Goetzl EJ, Wolkowitz OM, Srihari VH, Reus VI, Goetzl L, Kapogiannis D, Heninger GR, Mellon SH
• Correction: A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD.
  Molecular psychiatry 2021 Yang R, Wu GWY, Verhoeven JE, Gautam A, Reus VI, Kang JI, Flory JD, Abu-Amara D, PTSD Systems Biology Consortium, Hood L, Doyle FJ, Yehuda R, Marmar CR, Jett M, Hammamieh R, Mellon SH, Wolkowitz OM
• Serum brain-derived neurotrophic factor remains elevated after long term follow-up of combat veterans with chronic post-traumatic stress disorder.
  Psychoneuroendocrinology 2021 Wu GWY, Wolkowitz OM, Reus VI, Kang JI, Elnar M, Sarwal R, Flory JD, Abu-Amara D, Hammamieh R, Gautam A, Doyle FJ, Yehuda R, Marmar CR, Jett M, Mellon SH, SBPBC
• Utilization of machine learning for identifying symptom severity military-related PTSD subtypes and their biological correlates.
  Translational psychiatry 2021 Siegel CE, Laska EM, Lin Z, Xu M, Abu-Amara D, Jeffers MK, Qian M, Milton N, Flory JD, Hammamieh R, Daigle BJ, Gautam A, Dean KR, Reus VI, Wolkowitz OM, Mellon SH, Ressler KJ, Yehuda R, Wang K, Hood L…
• "GrimAge," an epigenetic predictor of mortality, is accelerated in major depressive disorder.
  Translational psychiatry 2021 Protsenko E, Yang R, Nier B, Reus V, Hammamieh R, Rampersaud R, Wu GWY, Hough CM, Epel E, Prather AA, Jett M, Gautam A, Mellon SH, Wolkowitz OM
• The DSM-5 Clinical and Public Health Committee (CPHC): operations, mechanics, controversies and recommendations.
  Psychological medicine 2020 McIntyre JS, Yager J, Everett A, Galanter CA, Lyness JM, Nininger J, Reus VI, Vergare M
• Genome-wide mapping of brain phenotypes in extended pedigrees with strong genetic loading for bipolar disorder.
  Molecular psychiatry 2020 Fears SC, Service SK, Kremeyer B, Araya C, Araya X, Bejarano J, Ramirez M, Castrillón G, Gomez-Franco J, Lopez MC, Montoya G, Montoya P, Aldana I, Teshiba TM, Al-Sharif NB, Jalbrzikowski M, Tishler TA…
• Pre-treatment allostatic load and metabolic dysregulation predict SSRI response in major depressive disorder: a preliminary report.
  Psychological medicine 2020 Hough CM, Bersani FS, Mellon SH, Morford AE, Lindqvist D, Reus VI, Epel ES, Wolkowitz OM
• A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD.
  Molecular psychiatry 2020 Yang R, Wu GWY, Verhoeven JE, Gautam A, Reus VI, Kang JI, Flory JD, Abu-Amara D, PTSD Systems Biology Consortium, Hood L, Doyle FJ, Yehuda R, Marmar CR, Jett M, Hammamieh R, Mellon SH, Wolkowitz OM
• Distinct and shared contributions of diagnosis and symptom domains to cognitive performance in severe mental illness in the Paisa population: a case-control study.
  The lancet. Psychiatry 2020 Service SK, Vargas Upegui C, Castaño Ramírez M, Port AM, Moore TM, Munoz Umanes M, Agudelo Arango LG, Díaz-Zuluaga AM, Melo Espejo J, López MC, Palacio JD, Ruiz Sánchez S, Valencia J, Teshiba TM, …
• Effect of Combat Exposure and Posttraumatic Stress Disorder on Telomere Length and Amygdala Volume.
  Biological psychiatry. Cognitive neuroscience and neuroimaging 2020 Kang JI, Mueller SG, Wu GWY, Lin J, Ng P, Yehuda R, Flory JD, Abu-Amara D, Reus VI, Gautam A, PTSD Systems Biology Consortium, Hammamieh R, Doyle FJ, Jett M, Marmar CR, Mellon SH, Wolkowitz OM
• Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates.
  Translational psychiatry 2020 Sul JH, Service SK, Huang AY, Ramensky V, Hwang SG, Teshiba TM, Park Y, Ori APS, Zhang Z, Mullins N, Olde Loohuis LM, Fears SC, Araya C, Araya X, Spesny M, Bejarano J, Ramirez M, Castrillón G, Gomez-…
• Vitamin D and inflammation in major depressive disorder.
  Journal of affective disorders 2020 Grudet C, Wolkowitz OM, Mellon SH, Malm J, Reus VI, Brundin L, Nier BM, Dhabhar FS, Hough CM, Westrin Å, Lindqvist D
• Genetic analysis of activity, brain and behavioral associations in extended families with heavy genetic loading for bipolar disorder.
  Psychological medicine 2019 Vreeker A, Fears SC, Service SK, Pagani L, Takahashi JS, Araya C, Araya X, Bejarano J, Lopez MC, Montoya G, Montoya CP, Teshiba TM, Escobar J, Cantor RM, López-Jaramillo C, Macaya G, Molina J, Reus VI…
• Shared Genetics of Psychiatric Disorders.
  F1000Research 2019 Fuller T, Reus V
• Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorder.
  Molecular psychiatry 2019 Dean KR, Hammamieh R, Mellon SH, Abu-Amara D, Flory JD, Guffanti G, Wang K, Daigle BJ, Gautam A, Lee I, Yang R, Almli LM, Bersani FS, Chakraborty N, Donohue D, Kerley K, Kim TK, Laska E, Young Lee M, …
• Accelerated aging in serious mental disorders.
  Current opinion in psychiatry 2019 Bersani FS, Mellon SH, Reus VI, Wolkowitz OM
• Cortisol, moderated by age, is associated with antidepressant treatment outcome and memory improvement in Major Depressive Disorder: A retrospective analysis.
  Psychoneuroendocrinology 2019 Jain FA, Connolly CG, Reus VI, Meyerhoff DJ, Yang TT, Mellon SH, Mackin S, Hough CM, Morford A, Wolkowitz OM
• The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder.
  Focus (American Psychiatric Publishing) 2019 Reus VI, Fochtmann LJ, Bukstein O, Eyler AE, Hilty DM, Horvitz-Lennon M, Mahoney J, Pasic J, Weaver M, Wills CD, McIntyre J, Kidd J, Yager J, Hong SH
• Metabolomic analysis of male combat veterans with post traumatic stress disorder.
  PloS one 2019 Mellon SH, Bersani FS, Lindqvist D, Hammamieh R, Donohue D, Dean K, Jett M, Yehuda R, Flory J, Reus VI, Bierer LM, Makotkine I, Abu Amara D, Henn Haase C, Coy M, Doyle FJ, Marmar C, Wolkowitz OM
• Plasma serotonin levels are associated with antidepressant response to SSRIs.
  Journal of affective disorders 2019 Holck A, Wolkowitz OM, Mellon SH, Reus VI, Nelson JC, Westrin Å, Lindqvist D
• Low serum brain-derived neurotrophic factor is associated with suicidal ideation in major depressive disorder.
  Psychiatry research 2019 Khan MS, Wu GWY, Reus VI, Hough CM, Lindqvist D, Westrin Å, Nier BM, Wolkowitz OM, Mellon SH
• Preface.
  Handbook of clinical neurology 2019 Reus VI, Lindqvist D
• Psychiatric manifestations of neurologic diseases: Etiology, phenomenology, and treatment.
  Handbook of clinical neurology 2019 Reus VI, Lindqvist D
• Understanding the Hidden Complexity of Latin American Population Isolates.
  American journal of human genetics 2018 Mooney JA, Huber CD, Service S, Sul JH, Marsden CD, Zhang Z, Sabatti C, Ruiz-Linares A, Bedoya G, Costa Rica/Colombia Consortium for Genetic Investigation of Bipolar Endophenotypes, Freimer N, …
• Predisposition to Neuropsychiatric Disease: Common Genetic Risk Factors.
  Focus (American Psychiatric Publishing) 2018 Reus VI
• Analysis of shared heritability in common disorders of the brain.
  Science (New York, N.Y.) 2018 Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, …
• Circulating cell-free mitochondrial DNA, but not leukocyte mitochondrial DNA copy number, is elevated in major depressive disorder.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2018 Lindqvist D, Wolkowitz OM, Picard M, Ohlsson L, Bersani FS, Fernström J, Westrin Å, Hough CM, Lin J, Reus VI, Epel ES, Mellon SH
• The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder.
  The American journal of psychiatry 2018 Reus VI, Fochtmann LJ, Bukstein O, Eyler AE, Hilty DM, Horvitz-Lennon M, Mahoney J, Pasic J, Weaver M, Wills CD, McIntyre J, Kidd J, Yager J, Hong SH
• So Where Are the Genes for Bipolar Disorder?
  Focus (American Psychiatric Publishing) 2017 Reus VI
• Increased circulating blood cell counts in combat-related PTSD: Associations with inflammation and PTSD severity.
  Psychiatry research 2017 Lindqvist D, Mellon SH, Dhabhar FS, Yehuda R, Grenon SM, Flory JD, Bierer LM, Abu-Amara D, Coy M, Makotkine I, Reus VI, Aschbacher K, Bersani FS, Marmar CR, Wolkowitz OM
• Telomere length is inversely correlated with urinary stress hormone levels in healthy controls but not in un-medicated depressed individuals-preliminary findings.
  Journal of psychosomatic research 2017 Fair B, Mellon SH, Epel ES, Lin J, Révész D, Verhoeven JE, Penninx BW, Reus VI, Rosser R, Hough CM, Mahan L, Burke HM, Blackburn EH, Wolkowitz OM
• Severity of anxiety- but not depression- is associated with oxidative stress in Major Depressive Disorder.
  Journal of affective disorders 2017 Steenkamp LR, Hough CM, Reus VI, Jain FA, Epel ES, James SJ, Morford AE, Mellon SH, Wolkowitz OM, Lindqvist D
• Biological predictors of insulin resistance associated with posttraumatic stress disorder in young military veterans.
  Psychoneuroendocrinology 2017 Blessing EM, Reus V, Mellon SH, Wolkowitz OM, Flory JD, Bierer L, Lindqvist D, Dhabhar F, Li M, Qian M, Abu-Amara D, Galatzer-Levy I, Yehuda R, Marmar CR
• The American Psychiatric Association Practice Guideline on the Use of Antipsychotics to Treat Agitation or Psychosis in Patients With Dementia.
  Focus (American Psychiatric Publishing) 2017 Reus VI, Fochtmann LJ, Eyler AE, Hilty DM, Horvitz-Lennon M, Jibson MD, Lopez OL, Mahoney J, Pasic J, Tan ZS, Wills CD, Rhoads R, Yager J
• Higher serum DHEA concentrations before and after SSRI treatment are associated with remission of major depression.
  Psychoneuroendocrinology 2016 Hough CM, Lindqvist D, Epel ES, Denis MS, Reus VI, Bersani FS, Rosser R, Mahan L, Burke HM, Wolkowitz OM, Mellon SH
• Oxidative stress, inflammation and treatment response in major depression.
  Psychoneuroendocrinology 2016 Lindqvist D, Dhabhar FS, James SJ, Hough CM, Jain FA, Bersani FS, Reus VI, Verhoeven JE, Epel ES, Mahan L, Rosser R, Wolkowitz OM, Mellon SH
• Increased pro-inflammatory milieu in combat related PTSD - A new cohort replication study.
  Brain, behavior, and immunity 2016 Lindqvist D, Dhabhar FS, Mellon SH, Yehuda R, Grenon SM, Flory JD, Bierer LM, Abu-Amara D, Coy M, Makotkine I, Reus VI, Bersani FS, Marmar CR, Wolkowitz OM
• Cortisol/DHEA ratio and hippocampal volume: A pilot study in major depression and healthy controls.
  Psychoneuroendocrinology 2016 Jin RO, Mason S, Mellon SH, Epel ES, Reus VI, Mahan L, Rosser RL, Hough CM, Burke HM, Mueller SG, Wolkowitz OM
• Leukocyte telomere length predicts SSRI response in major depressive disorder: A preliminary report.
  Molecular neuropsychiatry 2016 Hough CM, Bersani FS, Mellon SH, Epel ES, Reus VI, Lindqvist D, Lin J, Mahan L, Rosser R, Burke H, Coetzee J, Nelson JC, Blackburn EH, Wolkowitz OM
• Alterations in leukocyte transcriptional control pathway activity associated with major depressive disorder and antidepressant treatment.
  Translational psychiatry 2016 Mellon SH, Wolkowitz OM, Schonemann MD, Epel ES, Rosser R, Burke HB, Mahan L, Reus VI, Stamatiou D, Liew CC, Cole SW
• Characterization of Expression Quantitative Trait Loci in Pedigrees from Colombia and Costa Rica Ascertained for Bipolar Disorder.
  PLoS genetics 2016 Peterson CB, Service SK, Jasinska AJ, Gao F, Zelaya I, Teshiba TM, Bearden CE, Cantor RM, Reus VI, Macaya G, López-Jaramillo C, Bogomolov M, Benjamini Y, Eskin E, Coppola G, Freimer NB, Sabatti C
• The Role of Regional Conferences in Research Resident Career Development: The California Psychiatry Research Resident Retreat.
  Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2016 Besterman AD, Williams JK, Reus VI, Pato MT, Voglmaier SM, Mathews CA
• The American Psychiatric Association Practice Guideline on the Use of Antipsychotics to Treat Agitation or Psychosis in Patients With Dementia.
  The American journal of psychiatry 2016 Reus VI, Fochtmann LJ, Eyler AE, Hilty DM, Horvitz-Lennon M, Jibson MD, Lopez OL, Mahoney J, Pasic J, Tan ZS, Wills CD, Rhoads R, Yager J
• A population of atypical CD56(-)CD16(+) natural killer cells is expanded in PTSD and is associated with symptom severity.
  Brain, behavior, and immunity 2016 Bersani FS, Wolkowitz OM, Milush JM, Sinclair E, Eppling L, Aschbacher K, Lindqvist D, Yehuda R, Flory J, Bierer LM, Matokine I, Abu-Amara D, Reus VI, Coy M, Hough CM, Marmar CR, Mellon SH
• Genetic contributions to circadian activity rhythm and sleep pattern phenotypes in pedigrees segregating for severe bipolar disorder.
  Proceedings of the National Academy of Sciences of the United States of America 2015 Pagani L, St Clair PA, Teshiba TM, Service SK, Fears SC, Araya C, Araya X, Bejarano J, Ramirez M, Castrillón G, Gomez-Makhinson J, Lopez MC, Montoya G, Montoya CP, Aldana I, Navarro L, Freimer DG, …
• Association of dimensional psychological health measures with telomere length in male war veterans.
  Journal of affective disorders 2015 Bersani FS, Lindqvist D, Mellon SH, Epel ES, Yehuda R, Flory J, Henn-Hasse C, Bierer LM, Makotkine I, Abu-Amara D, Coy M, Reus VI, Lin J, Blackburn EH, Marmar C, Wolkowitz OM
• Global arginine bioavailability, a marker of nitric oxide synthetic capacity, is decreased in PTSD and correlated with symptom severity and markers of inflammation.
  Brain, behavior, and immunity 2015 Bersani FS, Wolkowitz OM, Lindqvist D, Yehuda R, Flory J, Bierer LM, Makotine I, Abu-Amara D, Coy M, Reus VI, Epel ES, Marmar C, Mellon SH
• Telomere length is inversely correlated with urinary stress hormone levels in healthy controls but not in un-medicated depressed individuals - Preliminary findings.
  Psychoneuroendocrinology 2015 Fair B, Mellon SH, Epel ES, Révész D, Verhoeven JE, Penninx BW, Reus VI, Mahan L, Hough C, Rosser R, Burke HM, Lin J, Blackburn EH, Wolkowitz OM
• Telomerase activation as a possible mechanism of action for psychopharmacological interventions.
  Drug discovery today 2015 Bersani FS, Lindqvist D, Mellon SH, Penninx BW, Verhoeven JE, Révész D, Reus VI, Wolkowitz OM
• Mitochondrial DNA copy number is reduced in male combat veterans with PTSD.
  Progress in neuro-psychopharmacology & biological psychiatry 2015 Bersani FS, Morley C, Lindqvist D, Epel ES, Picard M, Yehuda R, Flory J, Bierer LM, Makotkine I, Abu-Amara D, Coy M, Reus VI, Lin J, Blackburn EH, Marmar C, Wolkowitz OM, Mellon SH
• Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging.
  Neuroscience and biobehavioral reviews 2015 Lindqvist D, Epel ES, Mellon SH, Penninx BW, Révész D, Verhoeven JE, Reus VI, Lin J, Mahan L, Hough CM, Rosser R, Bersani FS, Blackburn EH, Wolkowitz OM
• Brain structure-function associations in multi-generational families genetically enriched for bipolar disorder.
  Brain : a journal of neurology 2015 Fears SC, Schür R, Sjouwerman R, Service SK, Araya C, Araya X, Bejarano J, Knowles E, Gomez-Makhinson J, Lopez MC, Aldana I, Teshiba TM, Abaryan Z, Al-Sharif NB, Navarro L, Tishler TA, Altshuler L, …
• PBMC telomerase activity, but not leukocyte telomere length, correlates with hippocampal volume in major depression.
  Psychiatry research 2015 Wolkowitz OM, Mellon SH, Lindqvist D, Epel ES, Blackburn EH, Lin J, Reus VI, Burke H, Rosser R, Mahan L, Mackin S, Yang T, Weiner M, Mueller S
• Smoking cessation abstinence goal in treatment-seeking smokers.
  Addictive behaviors 2014 Hall SM, Shi Y, Humfleet GL, Muñoz RF, Reus VI, Prochaska JJ
• Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.
  The American journal of psychiatry 2014 Yu D, Mathews CA, Scharf JM, Neale BM, Davis LK, Gamazon ER, Derks EM, Evans P, Edlund CK, Crane J, Fagerness JA, Osiecki L, Gallagher P, Gerber G, Haddad S, Illmann C, McGrath LM, Mayerfeld C, …
• Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls-preliminary findings.
  Psychiatry research 2014 Lindqvist D, Mueller S, Mellon SH, Su Y, Epel ES, Reus VI, Rosser R, Mahan L, Mackin RS, Yang TT, Wolkowitz OM
• Adverse childhood experiences and leukocyte telomere maintenance in depressed and healthy adults.
  Journal of affective disorders 2014 Chen SH, Epel ES, Mellon SH, Lin J, Reus VI, Rosser R, Kupferman E, Burke H, Mahan L, Blackburn EH, Wolkowitz OM
• Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.
  Journal of the American Academy of Child and Adolescent Psychiatry 2014 McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, Gallagher P, Fagerness JA, Barr CL,…
• Proinflammatory milieu in combat-related PTSD is independent of depression and early life stress.
  Brain, behavior, and immunity 2014 Lindqvist D, Wolkowitz OM, Mellon S, Yehuda R, Flory JD, Henn-Haase C, Bierer LM, Abu-Amara D, Coy M, Neylan TC, Makotkine I, Reus VI, Yan X, Taylor NM, Marmar CR, Dhabhar FS
• Smoking cessation outcomes among sexual and gender minority and nonminority smokers in extended smoking treatments.
  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2014 Grady ES, Humfleet GL, Delucchi KL, Reus VI, Muñoz RF, Hall SM
• Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees.
  JAMA psychiatry 2014 Fears SC, Service SK, Kremeyer B, Araya C, Araya X, Bejarano J, Ramirez M, Castrillón G, Gomez-Franco J, Lopez MC, Montoya G, Montoya P, Aldana I, Teshiba TM, Abaryan Z, Al-Sharif NB, Ericson M, …
• Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.
  PLoS genetics 2013 Davis LK, Yu D, Keenan CL, Gamazon ER, Konkashbaev AI, Derks EM, Neale BM, Yang J, Lee SH, Evans P, Barr CL, Bellodi L, Benarroch F, Berrio GB, Bienvenu OJ, Bloch MH, Blom RM, Bruun RD, Budman CL, …
• Eleven-year outcomes from an integrated residency program to train research psychiatrists.
  Academic medicine : journal of the Association of American Medical Colleges 2013 Tsai AC, Ordóñez AE, Reus VI, Mathews CA
• CNV analysis in Tourette syndrome implicates large genomic rearrangements in COL8A1 and NRXN1.
  PloS one 2013 Nag A, Bochukova EG, Kremeyer B, Campbell DD, Muller H, Valencia-Duarte AV, Cardona J, Rivas IC, Mesa SC, Cuartas M, Garcia J, Bedoya G, Cornejo W, Herrera LD, Romero R, Fournier E, Reus VI, Lowe TL, …
• Dysregulated relationship of inflammation and oxidative stress in major depression.
  Brain, behavior, and immunity 2012 Rawdin BJ, Mellon SH, Dhabhar FS, Epel ES, Puterman E, Su Y, Burke HM, Reus VI, Rosser R, Hamilton SP, Nelson JC, Wolkowitz OM
• Prevalence and clinical correlates of explosive outbursts in Tourette syndrome.
  Psychiatry research 2012 Chen K, Budman CL, Diego Herrera L, Witkin JE, Weiss NT, Lowe TL, Freimer NB, Reus VI, Mathews CA
• Genome-wide association study of Tourette's syndrome.
  Molecular psychiatry 2012 Scharf JM, Yu D, Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P, Gamazon E, Edlund CK, Service SK, Tikhomirov A, Osiecki L, Illmann C, Pluzhnikov A, Konkashbaev A, Davis LK, Han B, Crane J, …
• Genome-wide linkage analysis of obsessive-compulsive disorder implicates chromosome 1p36.
  Biological psychiatry 2012 Mathews CA, Badner JA, Andresen JM, Sheppard B, Himle JA, Grant JE, Williams KA, Chavira DA, Azzam A, Schwartz M, Reus VI, Kim SW, Cook EH, Hanna GL
• Serum BDNF levels before treatment predict SSRI response in depression.
  Progress in neuro-psychopharmacology & biological psychiatry 2011 Wolkowitz OM, Wolf J, Shelly W, Rosser R, Burke HM, Lerner GK, Reus VI, Nelson JC, Epel ES, Mellon SH
• Using extended cognitive behavioral treatment and medication to treat dependent smokers.
  American journal of public health 2011 Hall SM, Humfleet GL, Muñoz RF, Reus VI, Prochaska JJ, Robbins JA
• Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings.
  PloS one 2011 Wolkowitz OM, Mellon SH, Epel ES, Lin J, Dhabhar FS, Su Y, Reus VI, Rosser R, Burke HM, Kupferman E, Compagnone M, Nelson JC, Blackburn EH
• Immunogenicity and smoking-cessation outcomes for a novel nicotine immunotherapeutic.
  Clinical pharmacology and therapeutics 2011 Hatsukami DK, Jorenby DE, Gonzales D, Rigotti NA, Glover ED, Oncken CA, Tashkin DP, Reus VI, Akhavain RC, Fahim RE, Kessler PD, Niknian M, Kalnik MW, Rennard SI
• Resting leukocyte telomerase activity is elevated in major depression and predicts treatment response.
  Molecular psychiatry 2011 Wolkowitz OM, Mellon SH, Epel ES, Lin J, Reus VI, Rosser R, Burke H, Compagnone M, Nelson JC, Dhabhar FS, Blackburn EH
• Of sound mind and body: depression, disease, and accelerated aging.
  Dialogues in clinical neuroscience 2011 Wolkowitz OM, Reus VI, Mellon SH
• Recent trends in american board of psychiatry and neurology psychiatric subspecialties.
  Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2011 Faulkner LR, Juul D, Andrade NN, Brooks BA, Colenda CC, Guynn RW, Mrazek DA, Reus VI, Schneidman BS, Shaw KR
• Genome-wide linkage scan of bipolar disorder in a Colombian population isolate replicates Loci on chromosomes 7p21-22, 1p31, 16p12 and 21q21-22 and identifies a novel locus on chromosome 12q.
  Human heredity 2010 Kremeyer B, García J, Müller H, Burley MW, Herzberg I, Parra MV, Duque C, Vega J, Montoya P, López MC, Bedoya G, Reus V, Palacio C, López C, Ospina-Duque J, Freimer NB, Ruiz-Linares A
• Depression gets old fast: do stress and depression accelerate cell aging?
  Depression and anxiety 2010 Wolkowitz OM, Epel ES, Reus VI, Mellon SH
• A narrow and highly significant linkage signal for severe bipolar disorder in the chromosome 5q33 region in Latin American pedigrees.
  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009 Jasinska AJ, Service S, Jawaheer D, DeYoung J, Levinson M, Zhang Z, Kremeyer B, Muller H, Aldana I, Garcia J, Restrepo G, Lopez C, Palacio C, Duque C, Parra M, Vega J, Ortiz D, Bedoya G, Mathews C, …
• Glucocorticoids. Mood, memory, and mechanisms.
  Annals of the New York Academy of Sciences 2009 Wolkowitz OM, Burke H, Epel ES, Reus VI
• Longitudinal analysis of abstinence-specific social support and smoking cessation.
  Health psychology : official journal of the Division of Health Psychology, American Psychological Association 2009 Lawhon D, Humfleet GL, Hall SM, Muñoz RF, Reus VI
• Low serum IL-10 concentrations and loss of regulatory association between IL-6 and IL-10 in adults with major depression.
  Journal of psychiatric research 2009 Dhabhar FS, Burke HM, Epel ES, Mellon SH, Rosser R, Reus VI, Wolkowitz OM
• Extended treatment of older cigarette smokers.
  Addiction (Abingdon, England) 2009 Hall SM, Humfleet GL, Muñoz RF, Reus VI, Robbins JA, Prochaska JJ
• The ABCB1 transporter gene and antidepressant response.
  F1000 biology reports 2009 Peters EJ, Reus V, Hamilton SP
• Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS).
  Frontiers in neuroendocrinology 2008 Maninger N, Wolkowitz OM, Reus VI, Epel ES, Mellon SH
• Varenicline versus bupropion SR or placebo for smoking cessation: a pooled analysis.
  American journal of health behavior 2008 Nides M, Glover ED, Reus VI, Christen AG, Make BJ, Billing CB, Williams KE
• Multimodal techniques for smoking cessation: a review of their efficacy and utilisation and clinical practice guidelines.
  International journal of clinical practice 2008 Reus VI, Smith BJ
• Physical activity as a strategy for maintaining tobacco abstinence: a randomized trial.
  Preventive medicine 2008 Prochaska JJ, Hall SM, Humfleet G, Munoz RF, Reus V, Gorecki J, Hu D
• The ABPN Maintenance of Certification Program for psychiatrists: past history, current status, and future directions.
  Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2008 Faulkner LR, Tivnan PW, Winstead DK, Reus VI, Andrade NN, Brooks BA, Colenda CC, Mrazek DA, Reifler BV, Schneidman B
• Older versus younger treatment-seeking smokers: differences in smoking behavior, drug and alcohol use, and psychosocial and physical functioning.
  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2008 Hall SM, Humfleet GL, Gorecki JA, Muñoz RF, Reus VI, Prochaska JJ
• A comparative study of obsessive-compulsive disorder in Costa Rica and the United States.
  Depression and anxiety 2008 Chavira DA, Garrido H, Bagnarello M, Azzam A, Reus VI, Mathews CA
• Therapeutic drug monitoring of nortriptyline in smoking cessation: a multistudy analysis.
  Clinical pharmacology and therapeutics 2007 Mooney ME, Reus VI, Gorecki J, Hall SM, Humfleet GL, Muñoz RF, Delucchi K
• Belief about drug assignment and abstinence in treatment of cigarette smoking using nortriptyline.
  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2007 Hall SM, Gorecki JA, Reus VI, Humfleet GL, Muñoz RF
• Heritability and clinical features of multigenerational families with obsessive-compulsive disorder and hoarding.
  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007 Mathews CA, Nievergelt CM, Azzam A, Garrido H, Chavira DA, Wessel J, Bagnarello M, Reus VI, Schork NJ
• The pharmacogenetics research network: from SNP discovery to clinical drug response.
  Clinical pharmacology and therapeutics 2007 Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA,…
• Varenicline: new treatment with efficacy in smoking cessation.
  Drugs of today (Barcelona, Spain : 1998) 2007 Reus VI, Obach RS, Coe JW, Faessel H, Rollema H, Watsky E, Reeves K
• Overrepresentation of rare variants in a specific ethnic group may confuse interpretation of association analyses.
  Human molecular genetics 2006 Keen-Kim D, Mathews CA, Reus VI, Lowe TL, Herrera LD, Budman CL, Gross-Tsur V, Pulver AE, Bruun RD, Erenberg G, Naarden A, Sabatti C, Freimer NB
• Convergent linkage evidence from two Latin-American population isolates supports the presence of a susceptibility locus for bipolar disorder in 5q31-34.
  Human molecular genetics 2006 Herzberg I, Jasinska A, García J, Jawaheer D, Service S, Kremeyer B, Duque C, Parra MV, Vega J, Ortiz D, Carvajal L, Polanco G, Restrepo GJ, López C, Palacio C, Levinson M, Aldana I, Mathews C, …
• Results of a SNP genome screen in a large Costa Rican pedigree segregating for severe bipolar disorder.
  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2006 Service S, Molina J, Deyoung J, Jawaheer D, Aldana I, Vu T, Araya C, Araya X, Bejarano J, Fournier E, Ramirez M, Mathews CA, Davanzo P, Macaya G, Sandkuijl L, Sabatti C, Reus V, Freimer N
• Association between maternal smoking and increased symptom severity in Tourette's syndrome.
  The American journal of psychiatry 2006 Mathews CA, Bimson B, Lowe TL, Herrera LD, Budman CL, Erenberg G, Naarden A, Bruun RD, Freimer NB, Reus VI
• Catecholamine response to methamphetamine is related to glucocorticoid levels but not to pleasurable subjective response.
  Pharmacopsychiatry 2006 Harris DS, Reus VI, Wolkowitz O, Jacob P, Everhart ET, Wilson M, Mendelson JE, Jones RT
• Tic symptom profiles in subjects with Tourette Syndrome from two genetically isolated populations.
  Biological psychiatry 2006 Mathews CA, Jang KL, Herrera LD, Lowe TL, Budman CL, Erenberg G, Naarden A, Bruun RD, Schork NJ, Freimer NB, Reus VI
• Response to Zhang et al. (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16.
  Neuron 2005 Glatt CE, Carlson E, Taylor TR, Risch N, Reus VI, Schaefer CA
• Cost-effectiveness of bupropion, nortriptyline, and psychological intervention in smoking cessation.
  The journal of behavioral health services & research 2005 Hall SM, Lightwood JM, Humfleet GL, Bostrom A, Reus VI, Muñoz R
• Preliminary evidence of the association between the history of childhood attention-deficit/hyperactivity disorder and smoking treatment failure.
  Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2005 Humfleet GL, Prochaska JJ, Mengis M, Cullen J, Muñoz R, Reus V, Hall SM
• Repeated psychological stress testing in stimulant-dependent patients.
  Progress in neuro-psychopharmacology & biological psychiatry 2005 Harris DS, Reus VI, Wolkowitz OM, Mendelson JE, Jones RT
• Extended nortriptyline and psychological treatment for cigarette smoking.
  The American journal of psychiatry 2004 Hall SM, Humfleet GL, Reus VI, Muñoz RF, Cullen J
• Influences of mood, depression history, and treatment modality on outcomes in smoking cessation.
  Journal of consulting and clinical psychology 2004 Haas AL, Muñoz RF, Humfleet GL, Reus VI, Hall SM
• Self injurious behaviour in Tourette syndrome: correlates with impulsivity and impulse control.
  Journal of neurology, neurosurgery, and psychiatry 2004 Mathews CA, Waller J, Glidden D, Lowe TL, Herrera LD, Budman CL, Erenberg G, Naarden A, Bruun RD, Freimer NB, Reus VI
• Why genetic investigation of psychiatric disorders is so difficult.
  Current opinion in genetics & development 2004 Bearden CE, Reus VI, Freimer NB
• Chronic pregnenolone effects in normal humans: attenuation of benzodiazepine-induced sedation.
  Psychoneuroendocrinology 2004 Meieran SE, Reus VI, Webster R, Shafton R, Wolkowitz OM
• Genetic studies of neuropsychiatric disorders in Costa Rica: a model for the use of isolated populations.
  Psychiatric genetics 2004 Mathews CA, Reus VI, Bejarano J, Escamilla MA, Fournier E, Herrera LD, Lowe TL, McInnes LA, Molina J, Ophoff RA, Raventos H, Sandkuijl LA, Service SK, Spesny M, León PE, Freimer NB
• Genetic mapping using haplotype and model-free linkage analysis supports previous evidence for a locus predisposing to severe bipolar disorder at 5q31-33.
  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004 Hong KS, McInnes LA, Service SK, Song T, Lucas J, Silva S, Fournier E, León P, Molina J, Reus VI, Sandkuijl LA, Freimer NB
• Hormonal changes with cholesterol reduction: a double-blind pilot study.
  Journal of clinical pharmacy and therapeutics 2004 Ormiston T, Wolkowitz OM, Reus VI, Johnson R, Manfredi F
• Genetic linkage in bipolar disorder.
  CNS spectrums 2003 Mathews CA, Reus VI
• Behavioral implications of lowering cholesterol levels: a double-blind pilot study.
  Psychosomatics 2003 Ormiston T, Wolkowitz OM, Reus VI, Manfredi F
• Pharmacogenetics of monoamine transporters.
  Pharmacogenomics 2003 Glatt CE, Reus VI
• Neurotransmitters, neurosteroids and neurotrophins: new models of the pathophysiology and treatment of depression.
  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2003 Wolkowitz OM, Reus VI
• Altering cortisol level does not change the pleasurable effects of methamphetamine in humans.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003 Harris DS, Reus VI, Wolkowitz OM, Mendelson JE, Jones RT
• Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder.
  American journal of human genetics 2003 Segurado R, Detera-Wadleigh SD, Levinson DF, Lewis CM, Gill M, Nurnberger JI, Craddock N, DePaulo JR, Baron M, Gershon ES, Ekholm J, Cichon S, Turecki G, Claes S, Kelsoe JR, Schofield PR, Badenhop RF,…
• DHEA treatment of Alzheimer's disease: a randomized, double-blind, placebo-controlled study.
  Neurology 2003 Wolkowitz OM, Kramer JH, Reus VI, Costa MM, Yaffe K, Walton P, Raskind M, Peskind E, Newhouse P, Sack D, De Souza E, Sadowsky C, Roberts E, DHEA-Alzheimer's Disease Collaborative Research
• Benzodiazepines in schizophrenia: prefrontal cortex atrophy predicts clinical response to alprazolam augmentation.
  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2002 Seeley WW, Turetsky N, Reus VI, Wolkowitz OM
• Psychological intervention and antidepressant treatment in smoking cessation.
  Archives of general psychiatry 2002 Hall SM, Humfleet GL, Reus VI, Muñoz RF, Hartz DT, Maude-Griffin R
• Comorbidity of bipolar disorder and substance abuse in Costa Rica: pedigree- and population-based studies.
  Journal of affective disorders 2002 Escamilla MA, Batki S, Reus VI, Spesny M, Molina J, Service S, Vinogradov S, Neylan T, Mathews C, Meza L, Gallegos A, Montero AP, Cruz ML, Neuhaus J, Roche E, Smith L, Leon P, Freimer NB
• [Emergent topics of educators' perspectives on their own education for retired health care professionals].
  Puerto Rico health sciences journal 2002 Lourdes C, Reus V
• Genomewide linkage disequilibrium mapping of severe bipolar disorder in a population isolate.
  American journal of human genetics 2002 Ophoff RA, Escamilla MA, Service SK, Spesny M, Meshi DB, Poon W, Molina J, Fournier E, Gallegos A, Mathews C, Neylan T, Batki SL, Roche E, Ramirez M, Silva S, De Mille MC, Dong P, Leon PE, Reus VI, …
• Double-blind antiglucocorticoid treatment in schizophrenia and schizoaffective disorder: a pilot study.
  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2002 Marco EJ, Wolkowitz OM, Vinogradov S, Poole JH, Lichtmacher J, Reus VI
• Antiglucocorticoid drugs in the treatment of depression.
  Expert opinion on investigational drugs 2001 Reus VI, Wolkowitz OM
• Fine-scale mapping of a locus for severe bipolar mood disorder on chromosome 18p11.3 in the Costa Rican population.
  Proceedings of the National Academy of Sciences of the United States of America 2001 McInnes LA, Service SK, Reus VI, Barnes G, Charlat O, Jawahar S, Lewitzky S, Yang Q, Duong Q, Spesny M, Araya C, Araya X, Gallegos A, Meza L, Molina J, Ramirez R, Mendez R, Silva S, Fournier E, Batki …
• Cortisol levels predict cognitive impairment induced by electroconvulsive therapy.
  Biological psychiatry 2001 Neylan TC, Canick JD, Hall SE, Reus VI, Sapolsky RM, Wolkowitz OM
• Assortative mating in the affective disorders: a systematic review and meta-analysis.
  Comprehensive psychiatry 2001 Mathews CA, Reus VI
• Stress hormone-related psychopathology: pathophysiological and treatment implications.
  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2001 Wolkowitz OM, Epel ES, Reus VI
• Cultural influences on diagnosis and perception of Tourette syndrome in Costa Rica.
  Journal of the American Academy of Child and Adolescent Psychiatry 2001 Mathews CA, Herrera Amighetti LD, Lowe TL, van de Wetering BJ, Freimer NB, Reus VI
• Movement disorder, memory, psychiatric symptoms and serum DHEA levels in schizophrenic and schizoaffective patients.
  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2001 Harris DS, Wolkowitz OM, Reus VI
• Genome screening for linkage disequilibrium in a Costa Rican sample of patients with bipolar-I disorder: a follow-up study on chromosome 18.
  American journal of medical genetics 2001 Escamilla MA, McInnes LA, Service SK, Spesny M, Reus VI, Molina J, Gallegos A, Fournier E, Batki S, Neylan T, Matthews C, Vinogradov S, Roche E, Tyler DJ, Shimayoshi N, Mendez R, Ramirez R, Ramirez M,…
• An association study of bipolar mood disorder (type I) with the 5-HTTLPR serotonin transporter polymorphism in a human population isolate from Colombia.
  Neuroscience letters 2000 Ospina-Duque J, Duque C, Carvajal-Carmona L, Ortiz-Barrientos D, Soto I, Pineda N, Cuartas M, Calle J, Lopez C, Ochoa L, Garcia J, Gomez J, Agudelo A, Lozano M, Montoya G, Ospina A, Lopez M, Gallo A, …
• Possible interaction of tramadol and antidepressants.
  The American journal of psychiatry 2000 Reus VI, Rawitscher L
• Development of major depression after treatment for smoking cessation.
  The American journal of psychiatry 2000 Tsoh JY, Humfleet GL, Muñoz RF, Reus VI, Hartz DT, Hall SM
• Treatment of depression with antiglucocorticoid drugs.
  Psychosomatic medicine 1999 Wolkowitz OM, Reus VI
• Estrogen replacement therapy and cognitive decline in memory-impaired post-menopausal women.
  Biological psychiatry 1999 Costa MM, Reus VI, Wolkowitz OM, Manfredi F, Lieberman M
• Assessing the feasibility of linkage disequilibrium methods for mapping complex traits: an initial screen for bipolar disorder loci on chromosome 18.
  American journal of human genetics 1999 Escamilla MA, McInnes LA, Spesny M, Reus VI, Service SK, Shimayoshi N, Tyler DJ, Silva S, Molina J, Gallegos A, Meza L, Cruz ML, Batki S, Vinogradov S, Neylan T, Nguyen JB, Fournier E, Araya C, …
• Depressive symptoms and cognitive decline in nondemented elderly women: a prospective study.
  Archives of general psychiatry 1999 Yaffe K, Blackwell T, Gore R, Sands L, Reus V, Browner WS
• Antiglucocorticoid treatment of depression: double-blind ketoconazole.
  Biological psychiatry 1999 Wolkowitz OM, Reus VI, Chan T, Manfredi F, Raum W, Johnson R, Canick J
• Double-blind treatment of major depression with dehydroepiandrosterone.
  The American journal of psychiatry 1999 Wolkowitz OM, Reus VI, Keebler A, Nelson N, Friedland M, Brizendine L, Roberts E
• History of alcohol or drug problems, current use of alcohol or marijuana, and success in quitting smoking.
  Addictive behaviors 1999 Humfleet G, Muñoz R, Sees K, Reus V, Hall S
• Nortriptyline and cognitive-behavioral therapy in the treatment of cigarette smoking.
  Archives of general psychiatry 1998 Hall SM, Reus VI, Muñoz RF, Sees KL, Humfleet G, Hartz DT, Frederick S, Triffleman E
• Mapping genes for psychiatric disorders and behavioral traits.
  Current opinion in genetics & development 1998 McInnes LA, Reus VI, Freimer NB
• Cortisol and response to dexamethasone as predictors of withdrawal distress and abstinence success in smokers.
  Biological psychiatry 1998 Frederick SL, Reus VI, Ginsberg D, Hall SM, Munoz RF, Ellman G
• Selective alteration of personality and social behavior by serotonergic intervention.
  The American journal of psychiatry 1998 Knutson B, Wolkowitz OM, Cole SW, Chan T, Moore EA, Johnson RC, Terpstra J, Turner RA, Reus VI
• Glucocorticoid medication, memory and steroid psychosis in medical illness.
  Annals of the New York Academy of Sciences 1997 Wolkowitz OM, Reus VI, Canick J, Levin B, Lupien S
• Understanding the genetic basis of mood disorders: where do we stand?
  American journal of human genetics 1997 Reus VI, Freimer NB
• Olanzapine: a novel atypical neuroleptic agent.
  Lancet (London, England) 1997 Reus VI
• Dehydroepiandrosterone (DHEA) treatment of depression.
  Biological psychiatry 1997 Wolkowitz OM, Reus VI, Roberts E, Manfredi F, Chan T, Raum WJ, Ormiston S, Johnson R, Canick J, Brizendine L, Weingartner H
• Serotonergic intervention increases affiliative behavior in humans.
  Annals of the New York Academy of Sciences 1997 Knutson B, Cole S, Wolkowitz O, Reus V, Chan T, Moore E
• Antiglucocorticoid treatments in psychiatry.
  Psychoneuroendocrinology 1997 Reus VI, Wolkowitz OM, Frederick S
• A complete genome screen for genes predisposing to severe bipolar disorder in two Costa Rican pedigrees.
  Proceedings of the National Academy of Sciences of the United States of America 1996 McInnes LA, Escamilla MA, Service SK, Reus VI, Leon P, Silva S, Rojas E, Spesny M, Baharloo S, Blankenship K, Peterson A, Tyler D, Shimayoshi N, Tobey C, Batki S, Vinogradov S, Meza L, Gallegos A, …
• Mood management and nicotine gum in smoking treatment: a therapeutic contact and placebo-controlled study.
  Journal of consulting and clinical psychology 1996 Hall SM, Muñoz RF, Reus VI, Sees KL, Duncan C, Humfleet GL, Hartz DT
• Dexamethasone for depression.
  The American journal of psychiatry 1996 Wolkowitz OM, Reus VI, Manfredi F, Chan T, Ormiston S, Johnson R
• Attitudes towards bipolar disorder and predictive genetic testing among patients and providers.
  Journal of medical genetics 1996 Smith LB, Sapers B, Reus VI, Freimer NB
• Management of treatment-resistant unipolar and chronically depressed patients.
  The Psychiatric clinics of North America 1996 Reus VI
• An approach to investigating linkage for bipolar disorder using large Costa Rican pedigrees.
  American journal of medical genetics 1996 Freimer NB, Reus VI, Escamilla M, Spesny M, Smith L, Service S, Gallegos A, Meza L, Batki S, Vinogradov S, Leon P, Sandkuijl LA
• Use of linkage disequilibrium approaches to map genes for bipolar disorder in the Costa Rican population.
  American journal of medical genetics 1996 Escamilla MA, Spesny M, Reus VI, Gallegos A, Meza L, Molina J, Sandkuijl LA, Fournier E, Leon PE, Smith LB, Freimer NB
• Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-q23.
  Nature genetics 1996 Freimer NB, Reus VI, Escamilla MA, McInnes LA, Spesny M, Leon P, Service SK, Smith LB, Silva S, Rojas E, Gallegos A, Meza L, Fournier E, Baharloo S, Blankenship K, Tyler DJ, Batki S, Vinogradov S, …
• Behavioral genetics.
  The Western journal of medicine 1996 Reus VI
• Magnetic resonance spectroscopy and psychiatry.
  The Western journal of medicine 1996 Reus VI
• Psychiatry.
  The Western journal of medicine 1996 Reus VI
• Antidepressant and cognition-enhancing effects of DHEA in major depression.
  Annals of the New York Academy of Sciences 1995 Wolkowitz OM, Reus VI, Roberts E, Manfredi F, Chan T, Ormiston S, Johnson R, Canick J, Brizendine L, Weingartner H
• Cognitive-behavioral intervention increases abstinence rates for depressive-history smokers.
  Journal of consulting and clinical psychology 1994 Hall SM, Muñoz RF, Reus VI
• Are stress hormones and serotonin related to aggression in primates?
  Archives of general psychiatry 1994 Reus VI
• Mind and brain.
  Science (New York, N.Y.) 1993 Reus VI
• Nicotine, negative affect, and depression.
  Journal of consulting and clinical psychology 1993 Hall SM, Muñoz RF, Reus VI, Sees KL
• Rational polypharmacy in the treatment of mood disorders.
  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 1993 Reus VI
• Steroid modulation of human memory: biochemical correlates.
  Biological psychiatry 1993 Wolkowitz OM, Weingartner H, Rubinow DR, Jimerson D, Kling M, Berretini W, Thompson K, Breier A, Doran A, Reus VI
• Ketoconazole administration in hypercortisolemic depression.
  The American journal of psychiatry 1993 Wolkowitz OM, Reus VI, Manfredi F, Ingbar J, Brizendine L, Weingartner H
• Antiglucocorticoid strategies in hypercortisolemic states.
  Psychopharmacology bulletin 1992 Wolkowitz OM, Reus VI, Manfredi F, Ingbar J, Brizendine L
• Benzodiazepine augmentation of neuroleptics in treatment-resistant schizophrenia.
  Psychopharmacology bulletin 1992 Wolkowitz OM, Turetsky N, Reus VI, Hargreaves WA
• MRI deep white matter hyperintensity in a psychiatric population.
  Biological psychiatry 1991 Deicken RF, Reus VI, Manfredi L, Wolkowitz OM
• Cognitive effects of corticosteroids.
  The American journal of psychiatry 1990 Wolkowitz OM, Reus VI, Weingartner H, Thompson K, Breier A, Doran A, Rubinow D, Pickar D
• Pineal-adrenal interactions: the effect of acute pharmacological blockade of nocturnal melatonin secretion.
  Psychiatry research 1990 Demitrack MA, Lewy AJ, Reus VI
• Smoking cessation, depression and dysphoria.
  NIDA research monograph 1990 Hall SM, Munoz R, Reus V
• Behavioral aspects of thyroid disease in women.
  The Psychiatric clinics of North America 1989 Reus VI
• Genetics of mental illness.
  The Western journal of medicine 1987 Reus VI
• Cortisol and behaviorally conditioned histamine release.
  Annals of the New York Academy of Sciences 1987 Peeke HV, Ellman G, Dark K, Salfi M, Reus VI
• Neuroleptic dose: a statistical model for analyzing historical trends.
  Journal of psychiatric research 1987 Hargreaves WA, Zachary R, LeGoullon M, Binder R, Reus V
• Prediction of lithium dose: a mathematical alternative to the test-dose method.
  The Journal of clinical psychiatry 1986 Zetin M, Garber D, De Antonio M, Schlegel A, Feureisen S, Fieve R, Jewett C, Reus V, Huey LY
• A neuroanatomic perspective on state-dependent learning: the role of the striatum.
  Acta neurologica Scandinavica. Supplementum 1986 Reus VI
• Behavioral disturbances associated with endocrine disorders.
  Annual review of medicine 1986 Reus VI
• Habituation and cortisol dysregulation in depression.
  Biological psychiatry 1985 Reus VI, Peeke HV, Miner C
• Psychiatric symptoms in Behçet's syndrome.
  Psychosomatics 1985 Uhl V, Reus VI, Fromm JB
• Effects of carbamazepine on noradrenergic mechanisms in affectively ill patients.
  Psychopharmacology 1985 Post RM, Rubinow DR, Uhde TW, Ballenger JC, Lake CR, Linnoila M, Jimerson DC, Reus V
• Evidence for physiological effects of hypercortisolemia in psychiatric patients.
  Psychiatry research 1985 Reus VI, Miner C
• Toward an understanding of cortisol dysregulation in major depression: a review of studies of the dexamethasone suppression test and urinary free-cortisol.
  Psychiatric medicine 1985 Reus VI
• Effects of two doses of methylphenidate on verbal information processing in hyperactive children.
  Journal of clinical psychopharmacology 1984 Peeke S, Halliday R, Callaway E, Prael R, Reus V
• Electrophysiologic abnormalities in patients with eating disorders.
  Comprehensive psychiatry 1984 Grebb JA, Yingling CD, Reus VI
• Plasma L-tryptophan/neutral amino acid ratio and dexamethasone suppression in depression.
  Psychiatry research 1984 Joseph MS, Brewerton TD, Reus VI, Stebbins GT
• Sex differences and asymmetries of catecholamines: relation to turning preferences.
  Pharmacology, biochemistry, and behavior 1984 Dark KA, Ellman G, Peeke HV, Galin D, Reus VI
• Hormonal Mediation of the memory disorder in depression
  Drug Development Research 1984 Reus V
• Cognitive changes in schizoaffective patients.
  Archives of general psychiatry 1983 Reus VI
• Regulation of ACTH and cortisol in depression.
  Peptides 1983 Reus VI, Joseph M, Dallman M
• Hyperthyroidism may affect dexamethasone suppression.
  Journal of clinical psychopharmacology 1983 Reus VI
• Lithium carbonate and L-tryptophan in the treatment of bipolar and schizoaffective disorders.
  The American journal of psychiatry 1983 Brewerton TD, Reus VI
• Increased plasma MHPG in dexamethasone-resistant depressed patients.
  Archives of general psychiatry 1983 Jimerson DC, Insel TR, Reus VI, Kopin IJ
• Renal lithium clearance as a rapid and accurate predictor of maintenance dose.
  The American journal of psychiatry 1982 Norman KP, Cerrone KL, Reus VI
• How does methylphenidate (MP) affect information processing in man?
  Psychopharmacology bulletin 1982 Callaway E, Halliday R, Peeke S, Reus V
• The "atypical" clinical picture of adolescent mania.
  The American journal of psychiatry 1982 Ballenger JC, Reus VI, Post RM
• Pituitary-adrenal disinhibition as the independent variable in the assessment of behavioral symptoms.
  Biological psychiatry 1982 Reus VI
• ACTH levels after the dexamethasone suppression test in depression.
  The New England journal of medicine 1982 Reus VI, Joseph MS, Dallman MF
• Role of opioid peptides in disorders of attention in psychopathology.
  Annals of the New York Academy of Sciences 1982 Buchsbaum MS, Reus VI, Davis GC, Holcomb HH, Cappelletti J, Silberman E
• Heterogeneity of amphetamine response in depressed patients.
  The American journal of psychiatry 1981 Silberman EK, Reus VI, Jimerson DC, Lynott AM, Post RM
• Psychiatry-epitomes of progress: screening for endogenous depression: the dexamethasone suppression test.
  The Western journal of medicine 1981 Reus VI
• Failure of naloxone to reduce manic symptoms.
  The American journal of psychiatry 1980 Davis GC, Extein I, Reus VI, Hamilton W, Post RM, Goodwin FK, Bunney WE
• Neuropeptide modulation of opiate and ethanol tolerance and dependence.
  Medical hypotheses 1980 Reus VI
• Effect of piribedil (ET-495) on plasma norepinephrine: relationship to antidepressant response.
  Communications in psychopharmacology 1980 Reus VI, Lake CR, Post RM
• Clinical implications of state-dependent learning.
  The American journal of psychiatry 1979 Reus VI, Weingartner H, Post RM
• Behavioral side effects of medical drugs.
  Primary care 1979 Reus VI
• Effect of lithium carbonate on memory processes of bipolar affectively ill patients.
  Psychopharmacology 1979 Reus VI, Targum SD, Weingartner H, Post RM
• Lithium-induced thyrotoxicosis.
  The American journal of psychiatry 1979 Reus VI, Gold P, Post R
• d-Amphetamine: effects on memory in a depressed population.
  Biological psychiatry 1979 Reus VI, Silberman E, Post RM, Weingartner H
• Vasopressin in affective illness.
  Lancet (London, England) 1978 Gold PW, Goodwin FK, Reus VI
• An examination of the federal psychiatric training grant peer review process.
  The American journal of psychiatry 1977 Wilkinson CB, Reus VI
• Research training in psychiatry.
  The American journal of psychiatry 1977 Pardes H, Freedman AM, Reus V
• The development of criteria for evaluating psychiatric education programs.
  Archives of general psychiatry 1976 Eaton JS, Haas MR, Abraham AS, Reus VI, Goldberg R
• Use of in vivo consultation in dyadic psychotherapy.
  Psychotherapy (Chicago, Ill.) 1976 Neill JR, Reus V